Focused Ultrasound Therapy
Focused ultrasound is an early-stage, non-invasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with addiction. This novel technology focuses beams of ultrasound energy precisely and accurately on targets deep in the brain, known be involved in manifestation of addiction, without damaging surrounding normal tissue. Where the beams converge, the ultrasound can produce biological effects that can potentially help with addiction. One mechanism is thermal ablation of target tissue and the second is neuromodulation (altering the effects of neural impulses). Though still in the very early stages of development, for certain patients, these techniques have potential to provide a noninvasive, and more effective treatment for addiction.
As opioid addiction has proceeded to clinical trialsis a major specific problem currently, please see the “Addiction, Opioid” heading for more information about this topic.
- Focused ultrasound can reach the desired target(s) without damaging surrounding tissue.
- It can be repeated, if necessary.
At the present time, there are no clinical trials recruiting patients for focused ultrasound treatment for addiction.
Regulatory Approval and Reimbursement
Focused ultrasound treatment for addiction is not yet approved by regulatory bodies or covered by medical insurance companies.
Mooney SJ, Nobrega JN, Levitt AJ, Hynynen K. Antidepressant effects of focused ultrasound induced blood-brain-barrier opening. Behav Brain Res. 2018 Apr 16;342:57-61. doi: 10.1016/j.bbr.2018.01.004. Epub 2018 Jan 8.