Intellectual Property

Starting in 2020, the Foundation began tracking all new focused ultrasound patents issued by the US Patent Office.  This page is updated on a quarterly basis.

For companies seeking intellectual property advice, we have also provided a curated a list of IP/regulatory lawyers.

January 1, 2020 – March 31, 2025

The list below was compiled using the United States Patent and Trademark Office’s database. 

Patents Issued 

Patent Number: US12251451
Patent Title: Emulsion For Ultrasound Ablation Surgery
Patent Owner: Avignon Université, Centre National De La Recherche Scientifique—CNRS, Institut National De La Santé Et De La Recherche Médicale, Sorbonne Université, Universite De Montpellier, Ecole Nationale Superieure Se Chimie De Montpellier
Date Issued: March 18, 2025

Patent Number: US12251583
Patent Title: Cavitation Based Tissue Removal Device Using Focused Ultrasound
Patent Owner: Korea Institute of Science ad Technology
Date Issued: March 18, 2025

Patent Number: US12233288
Patent Title: Motion Based Methods For Cosmetic Ultrasound Treatments
Patent Owner: Venusa Group LLC
Date Issued: February 25, 2025

Patent Number: US12220602
Patent Title: Histotripsy Therapy Systems And Methods For The Treatment Of Brain Tissue
Patent Owner: The Regents of the University of Michigan
Date Issued: February 11, 2025

Patent Number: US12220603
Patent Title: High-intensity Focused Ultrasound Apparatus And Control Method
Patent Owner: Ultrasound Assisted Medtech PTE. LTD. (China)
Date Issued: February 11, 2025

Patent Number: US12207930
Patent Title: Non-invasive Transcranial Stimulation System And Method Using Pre-recorded Neurostimulation Data
Patent Owner: Xerox Corporation
Date Issued: January 28, 2025

Patent Number: US12186594
Patent Title: Pulsed Focused Ultrasound Therapy For Treatment Of Pancreatic Disorders
Patent Owner: The Board of Trustees of the Leland Stanford Junior University
Date Issued: January 7, 2025

Patent Number: US 12168055 B2
Patent Title: Sonosensitization
Patent Owner: SonalaSense, Inc.
Date Issued: December 17, 2024

Patent Number: US 12133728 B2
Patent Title: Systems And Methods For Evaluating Tissue Of A Subject
Patent Owner: UNIVERSITY OF WASHINGTON FRED HUTCHINSON CANCER RESEARCH CENTER
Date Issued: November 5, 2024

Patent Number: US 12133994 B2
Patent Title: Focused Ultrasound Device And Image Transducer Protection Method
Patent Owner: IMGT CO., LTD.
Date Issued: November 5, 2024

Patent Number: US 12127887 B2
Patent Title: Method For Obtaining Elastic Properties Of A Soft Solid, Which Uses Acoustic Vortices
Patent Owner: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS UNIVERSITAT POLITÉCNICA DE VALÉNCIA
Date Issued: October 29, 2024

Patent Number: US 12127979 B2
Patent Title: Robotic Cataract Surgery Using Focused Ultrasound
Patent Owner: Johnson & Johnson Surgical Vision, Inc.
Date Issued: October 29, 2024

Patent Number: 12096980
Patent Title: Mediator-free universal laser light amplification with coaxial propagating focused ultrasound and system
Patent Owner: Phononz Inc
Date Issued: September 24, 2024

Patent Number: 12090347
Patent Title: High intensity focused ultrasonic device with vertical assembly structure
Patent Owner: Ecleo Co., Ltd.
Date Issued: September 17, 2024

Patent Number: 12064649
Patent Title: Ultrasound probe for treating external body tissues
Patent Owner: Biotec Italia S.R.L.
Date Issued: August 20, 2024

Patent Number: 12059583
Patent Title: Ultrasonic transducer and focused ultrasound treatment device
Patent Owner: Chongqing Haifu Medical Technology Co., Ltd.
Date Issued: August 13, 2024

Patent Number: 12053198
Patent Title: Apparatus and method for precise mechanical tissue ablation using pressure modulated focused ultrasound
Patent Owner: Korea Institute Of Science And Technology
Date Issued: August 6, 2024

Patent Number: 12053653
Patent Title: Focused ultrasound device and method for setting order of focused ultrasound treatment thereof
Patent Owner: IMGT Co., Ltd.
Date Issued: August 6, 2024

Patent Number: 12054788
Patent Title: Methods and systems for noninvasive and localized brain liquid biopsy using focused ultrasound
Patent Owner: Washington University
Date Issued: August 6, 2024

Patent Number: 12023055
Patent Title: Balloon catheter system assisted by ultrasound and microbubbles and method for vasodilation
Patent Owner: National Tsing Hua University
Date Issued: July 2, 2024

  • Patent Number: 12016726B2
  • Patent Title: Flexible ultrasound transducer and method for manufacturing the same
  • Patent Owner: Korea Institute Of Science And Technology
  • Date Issued: June 24, 2024

  • Patent Number: 12011619B2
  • Patent Title: Low intensity focused ultrasound for treating cancer and metastasis
  • Patent Owner: Montefiore Medical Center, Albert Einstein College Of Medicine
  • Date Issued: June 18, 2024

  • Patent Number: 11998764B2
  • Patent Title: Extracorporeal focused ultrasound treatment device for pelvic disease
  • Patent Owner: Chongqing Haifu Medical Technology Co., Ltd.
  • Date Issued: June 4, 2024

  • Patent Number: 11980778B2
  • Patent Title: Histotripsy systems and methods
  • Patent Owner: Histosonics, Inc.
  • Date Issued: May 14, 2024

  • Patent Number: 11957936B2
  • Patent Title: Passive wire reflectors for improved image quality in MR-guided focused ultrasound
  • Patent Owner: Vanderbilt University
  • Date Issued: April 16, 2024

  • Patent Number: 11944849B2
  • Patent Title: Title Systems and methods for combined cosmetic treatment of cellulite with ultrasound
  • Patent Owner: Ulthera, Inc.
  • Date Issued: April 2, 2024

  • Patent Number: 11896853
  • Patent Title: Transrectal Ultrasound Probe For Boiling Histotripsy Ablation Of Prostate, And Associated Systems And Methods
  • Patent Owner: University of Washington
  • Date Issued: February 13, 2024

  • Patent Number: 11878190
  • Patent Title: Triboelectric Generator Including Nano-composite Time-limited Via Selective Ultrasound Application Thereto And Neurostimulation Therapy Device Using The Same
  • Patent Owner: ENERGY MINING CO., LTD (Korea)
  • Date Issued: January 23, 2024

  • Patent Number: 11872415
  • Patent Title: Device System And Method For Trans-cranial Focused Ultrasound Without Hair Shaving
  • Patent Owner: John Moshe Gomori
  • Date Issued: January 16, 2024

  • Patent Number: 11857813
  • Patent Title: High Intensity Focused Ultrasound Systems For Treating Tissue
  • Patent Owner: University of Washington
  • Date Issued: January 2, 2024

  • Patent Number: 11857807
  • Patent Title: Simulation-based Drug Treatment Planning
  • Patent Owner: INSIGHTEC, LTD.
  • Date Issued: January 2, 2024

  • Patent Number: 11826205
  • Patent Title: Ultrasound Imaging Method And System
  • Patent Owner: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
  • Date Issued: November 28, 2023

  • Patent Number: 11819712
  • Patent Title: Histotripsy Using Very Short Ultrasound Pulses
  • Patent Owner: The Regents of the University of Michigan
  • Date Issued: November 21, 2023

  • Patent Number: 11813484
  • Patent Title: Histotripsy Systems And Methods
  • Patent Owner: HistoSonics, Inc.
  • Date Issued: November 14, 2023

  • Patent Number: 11813485
  • Patent Title: Systems And Methods For Histotripsy Immunosensitization
  • Patent Owner: The Regents of the University of Michigan; The United States Government as represented by the Department of Veterans Affairs
  • Date Issued: November 14, 2023

  • Patent Number: 11806553
  • Patent Title: Transducer Assembly For Generating Focused Ultrasound
  • Patent Owner: DALHOUSIE UNIVERSITY (Halifax, CA)
  • Date Issued: November 7, 2023

  • Patent Number: 11801401
  • Patent Title: High Intensity Focused Ultrasound Transducer Optimization
  • Patent Owner: Profound Medical Inc.
  • Date Issued: October 31, 2023

  • Patent Number: 11801400
  • Patent Title: Therapy Apparatus For Treating Tissue By The Emission Of Remote Crossed Focused Ultrasound Waves
  • Patent Owner: EDAP TMS FRANCE; INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDECALE (INSERM); UNIVERSITE CLAUDE BERNARD LYON 1; CENTRE LEON BERARD
  • Date Issued: October 31, 2023

  • Patent Number: 11786468
  • Patent Title: Nanoparticles
  • Patent Owner: King’s College, London
  • Date Issued: October 17, 2023

  • Patent Number: 11786215
  • Patent Title: Methods Of Detecting, Measuring, Or Imaging A Concentration Or Location Of A Therapeutic Agent
  • Patent Owner: Washington University
  • Date Issued: October 17, 2023

  • Patent Number: 11752687
  • Patent Title: Method For 3D Printing And 3D Printer Using Ultrasound
  • Patent Owner: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
  • Date Issued: September 12, 2023

  • Patent Number: 11730960
  • Patent Title: Ultrasound Systems And Associated Devices And Methods For Modulating Brain Activity
  • Patent Owner: ATTUNE NEUROSCIENCES, INC. (Menlo Park, CA)
  • Date Issued: August 22, 2023

  • Patent Number: 11691032
  • Patent Title: Cartridge For High Intensity Focused Ultrasound Device Comprising Piezoelectric Linear Motor And Piezoelectric Linear Motor
  • Patent Owner: ECO DM LAB Co., Ltd. (South Korea)
  • Date Issued: July 4, 2023

  • Patent Number: 11667975
  • Patent Title: Methods And Systems For Noninvasive And Localized Brain Liquid Biopsy Using Focused Ultrasound
  • Patent Owner: Washington University
  • Date Issued: June 6, 2023

  • Patent Number: 11653839
  • Patent Title: Devices And Methods For Fractionated Photoacoustic Flow Cytometry
  • Patent Owner: BioVentures, LLC (Arkansas, US)
  • Date Issued: May 23, 2023

  • Patent Number: 11644520
  • Patent Title: Systems And Methods For Magnetic Resonance Based Skull Thermometry
  • Patent Owner: University of Virginia Patent Foundation
  • Date Issued: May 9, 2023

  • Patent Number: 11596379
  • Patent Title: Ultrasound Treatment Device For HIFU And Ultrasound Image, And Control Method Therefor
  • Patent Owner: Sogang University Research Foundation (Korea)
  • Date Issued: March 7, 2023

  • Patent Number: 11596812
  • Patent Title: Wearable Transcranial Dual-mode Ultrasound Transducers For Neuromodulation
  • Patent Owner: Regents of the University of Minnesota
  • Date Issued: March 7, 2023

  • Patent Number: 11577096
  • Patent Title: Systems And Methods For Modulation And Mapping Of Brain Tissue Using An Ultrasound Assembly
  • Patent Owner: The Trustees of Columbia University in the City of New York
  • Date Issued: February 14, 2023

  • Patent Number: 11580945
  • Patent Title: Confinement Or Movement Of An Object Using Focused Ultrasound Waves To Generate An Ultrasound Intensity Well
  • Patent Owner: University of Washington
  • Date Issued: February 14, 2023

  • Patent Number: 11554166
  • Patent Title: Immunogenic Treatment Of Cancer
  • Patent Owner: Immodulon Therapeutics Limited (London)
  • Date Issued: January 17, 2023

  • Patent Number: 11524183
  • Patent Title: System, Apparatus, And Method For Delivering Ultrasound
  • Patent Owner: Sonoblate Corp
  • Date Issued: December 13, 2022

  • Patent Number: 11524182
  • Patent Title: Non-invasive Treatment System Using Intermedium
  • Patent Owner: Korea Institute of Science and Technology
  • Date Issued: December 13, 2022

  • Patent Number: 11497465
  • Patent Title: Method for Treatment of a Vascular Lesion
  • Patent Owner: Bard Peripheral Vascular, Inc. (Franklin Lakes, NJ)
  • Date Issued: November 15, 2022

  • Patent Number: 11491352
  • Patent Title: High-low Intensity Focused Ultrasound Treatment Apparatus
  • Patent Owner: Korea Institute of Science and Technology
  • Date Issued: November 8, 2022

  • Patent Number: 11484207
  • Patent Title: Method and System for Correcting Focus Location in Magnetic Resonance Guided FUS Surgery
  • Patent Owner: Soochow University (Taipei)
  • Date Issued: November 1, 2022

  • Patent Number: 11471705
  • Patent Title: HIFU Skin Care Device and Cartridge
  • Patent Owner: Medicon Co, Ltd (Wonju-Si, Korea)
  • Date Issued: October 18, 2022

  • Patent Number: 11464482
  • Patent Title: System And Method For Measuring And Correcting Ultrasound Phase Distortions Induced By Aberrating Media
  • Patent Owner: Sunnybrook Research Institute (Toronto)
  • Date Issued: October 11, 2022

  • Patent Number: 11,452,887
  • Patent Title: Ultrasonic Stimulation Device Using Guide Framework
  • Patent Owner: Korea Institute of Science and Technology
  • Date Issued: September 27, 2022

  • Patent Number: 11,439,364
  • Patent Title: Ultrasonic Imaging Devices, Systems and Methods
  • Patent Owner: BFLY Operations, Inc (US)
  • Date Issued: September 13, 2022

  • Patent Number: 11,406,848
  • Patent Title: Ultrasonic Therapy Device Using HIFU And Control Method Thereof
  • Patent Owner: Sogang University Research Foundation (Seoul)
  • Date Issued: August 9, 2022

  • Patent Number: 11,383,106
  • Patent Title: Ultrasound Therapy System
  • Patent Owner: National Institute of Advanced Industrial Science and Technology (Tokyo)
  • Date Issued: July 12, 2022

  • Patent Number: 11,376,074
  • Patent Title: Simulation-based Focused-ultrasound Treatment Planning
  • Patent Owner: Insightec LTD
  • Date Issued: July 5, 2022

  • Patent Number: 11,358,007
  • Patent Title: Ultrasound frequency and microbubble size optimization in microbubble-enhanced ultrasound treatment
  • Patent Owner: De Picciotto, Rafi; Grinfeld, Javier; Levy, Yoav
  • Date Issued: June 14, 2022

  • Patent Number: 11,318,193
  • Patent Title: Immunogenic treatment of cancer
  • Patent Owner: Akle, Charles; Mudan, Satvinder; Grange, John
  • Date Issued: May 3, 2022

  • Patent Number: 11,305,133
  • Patent Title: Efficient acoustic energy transfer through skull via excitation of Lamb waves
  • Patent Owner: Khuri-Yakub, Butrus T.; Firouzi, Kamyar
  • Date Issued: April 19, 2022

  • Patent Number: 11,273,331
  • Patent Title: Systems and methods for high intensity focused ultrasound
  • Patent Owner: Jang, Ji Hoon; Stedman, George Quintin; Rasmussen, Morten Fischer; Ergun, Arif Sanli; Khuri-Yakub, Butrus T.
  • Date Issued: March 15, 2022

  • Patent Number: 11,260,249
  • Patent Title: System, apparatus and method for high intensity focused ultrasound and tissue healing activation
  • Patent Owner: Carol, Mark
  • Date Issued: March 1, 2022

  • Patent Number: 11,259,784
  • Patent Title: Ultrasound imaging method and system
  • Patent Owner: Du, Yigang; Fan, Rui; Li, Yong
  • Date Issued: March 1, 2022

  • Patent Number: 11,255,965
  • Patent Title: Systems and methods for ultrasound beamforming using coherently compounded Fresnel focusing
  • Patent Owner: Brown, Jeremy; Samson, Christopher; Latham, Katherine
  • Date Issued: February 22, 2022

  • Patent Number: 11229810
  • Patent Title: Methods and systems for producing neuronal lesions using magnetic resonance and acoustic energy
  • Patent Owner: Kevin S. Lee, Edward H. Bertram, Max Wintermark
  • Date Issued: January 25, 2022

  • Patent Number: 11,228,276
  • Patent Title: Ultrasound cleaning system for solar panels
  • Patent Owner: Elseddawy, Ahmed; Sindi, Hatem; Azzouz, Maher
  • Date Issued: January 18, 2022

  • Patent Number: 11,191,980
  • Patent Title: Automated magnetic resonance image segmentation for ultrasound thermal therapy control
  • Patent Owner: Falkovskiy, Pavel
  • Date Issued: December 7, 2021

  • Patent Number: 11,156,686
  • Patent Title: Acoustic radiation force imaging
  • Patent Owner: Mougenot, Charles
  • Date Issued: October 26, 2021

  • Patent Number: 11,134,846
  • Patent Title: Methods and systems for modifying electrical currents in neuronal circuits
  • Patent Owner: Yoo, Seung-Schik; Bystritsky, Alexander; McDannold, Nathan; Jolesz, Ferenc A.
  • Date Issued: October 5, 2021

  • Patent Number: 11,116,405
  • Patent Title: High-intensity focused ultrasound for heating a target zone larger than the electronic focusing zone
  • Patent Owner: Partanen, Ari Ilkka Mikael; Dreher, Matthew Robert; Yarmolenko, Pavel Sergeyevich; Wood, Bradford Johns; Carvajal Gallardo, Elma Natalia
  • Date Issued: September 14, 2021

  • Patent Number: 11,058,900
  • Patent Title: Methods and apparatus for treating a cervix with ultrasound energy
  • Patent Owner: Towe, Bruce C.; Garfield, Robert E.; Shi, Shao-Qing
  • Date Issued: July 13, 2021

  • Patent Number: 11,052,267
  • Patent Title: Back pain treatment using microwave sources
  • Patent Owner: Diederich, Chris J.; Lotz, Jeffrey C.; Nau, Will; Bradford, David S.
  • Date Issued: July 6, 2021

  • Patent Number: 11,020,617
  • Patent Title: Methods and systems for peripheral nerve modulation using non ablative focused ultrasound with electromyography (EMG) monitoring
  • Patent Owner: Konofagou; Elisa E., Downs; Matthew, Lee; Stephen, Kim; Min Gon, Kamimura; Hermes Arytto Salles
  • Date Issued: June 1, 2021

  • Patent Number: 11,013,938
  • Patent Title: Methods and systems for peripheral nerve modulation using non ablative focused ultrasound with electromyography (EMG) monitoring
  • Patent Owner: Konofagou; Elisa E., Downs; Matthew
  • Date Issued: May 25, 2021

  • Patent Number: 10,974,077
  • Patent Title: Low intensity focused ultrasound for treating cancer and metastasis
  • Patent Owner: Guha; Chandan, Barry; Stephen, Macian; Fernando
  • Date Issued: April 13, 2021

  • Patent Number: 10,959,768
  • Patent Title: Non-invasive methods for modifying tissue to facilitate treatment
  • Patent Owner: Slivka; Michael, et. al. (DePuy Synthes Products, Inc.)
  • Date Issued: March 30, 2021

  • Patent Number: 10,945,610
  • Patent Title: Devices and methods for fractionated photoacoustic flow cytometry
  • Patent Owner: Zharov; Vladimir Pavlovich (BioVentures, LLC)
  • Date Issued: March 16, 2021

  • Patent Number: 10,925,629
  • Patent Title: Transducer for therapeutic ultrasound apparatus and method
  • Patent Owner: Mitchell; Stuart B., et. al. (Novuson Surgical, Inc.)
  • Date Issued: February 23, 2021

  • Patent Number: 10,898,254
  • Patent Title: Implantable thermal treatment method and apparatus
  • Patent Owner: Diederich; Chris J, et. al. (The Regents of the University of California)
  • Date Issued: January 26, 2021

  • Patent Number: 10,856,847
  • Patent Title: Monolithic ultrasonic imaging devices, systems and methods
  • Patent Owner: Rothberg; Jonathan M, et. al. (Butterfly Network, Inc.)
  • Date Issued: December 8, 2020

  • Patent Number: 10,751,125
  • Patent Title: Simulation-based focused-ultrasound treatment planning
  • Patent Owner: Levy; Yoav, et. al. (Insightec)
  • Date Issued: August 25, 2020

  • Patent Number: 210,736,603
  • Patent Title: Method and apparatus for treating valvular disease
  • Patent Owner: Messas; Emmanuel, et. al. (Cardiawave)
  • Date Issued: August 11, 2020

  • Patent Number: 310,722,137
  • Patent Title: Systems and methods for accelerated MR thermometry
  • Patent Owner: Fielden; Samuel, et. al. (University of Virginia Patent Foundation, The Board of Trustees of the Leland Stanford Junior University)
  • Date Issued: July 28, 2020

  • Patent Number: 410,716,958
  • Patent Title: Method for operating a medical robot, a medical robot, and a medical workstation
  • Patent Owner: Neff; Thomas
  • Date Issued: July 21, 2020

  • Patent Number: 510,710,873
  • Patent Title: Complementary metal oxide semiconductor (CMOS) ultrasonic transducers and methods for forming the same
  • Patent Owner: Rothberg; Jonathan M., et. al. (Butterfly Network, Inc.)
  • Date Issued: July 14, 2020

  • Patent Number: 10,603,520
  • Patent Title: Therapeutic treatment device
  • Patent Owner: Yon, Sylvain, et al. (Theraclion)
  • Date Issued: March 31, 2020

  • Patent Number: 10,603,522
  • Patent Title: Method of treating back pain with microwave sources
  • Patent Owner: Diederich, Chris, et al. (University of California)
  • Date Issued: March 31, 2020

  • Patent Number: 10,595,828
  • Patent Title: Probe, ultrasound imaging apparatus and controlling method of the ultrasound imaging apparatus.
  • Patent Owner: Liberman; Alexander, et al. (Samsung Electronics, University of California)
  • Date Issued: March 24, 2020

  • Patent Number: 10,589,131
  • Patent Title: Methods of delivering chemical denervation to the vertebral body
  • Patent Owner: Diederich, Chris, et al. (University of California)
  • Date Issued: March 17, 2020

  • Patent Number: 10,542,963
  • Patent Title: Ultrasound phantom for focused ultrasound, method for manufacturing the same, biomimetic hydrogel phantom, method for manufacturing the same, discoloring method and drug delivering method using the same
  • Patent Owner: Kim, Se Hwa, et al. (Korea Research Institute of Standards and Science (KR))
  • Date Issued: January 28, 2020

  • Patent Number: 10,535,332
  • Patent Title: Confinement or movement of an object using focused ultrasound waves to generate an ultrasound intensity well
  • Patent Owner: Maxwell, Adam D., et al. (University of Washington)
  • Date Issued: January 14, 2020

List of Intellectual Property Lawyers

For companies seeking intellectual property advice, below is a curated a list of IP/regulatory lawyers with extensive experience in the medical device industry and the relevant contact information.

Cooley

Roberts Calderon Safran & Cole PC

  • Andrew M. Calderon, Head of Mechanical Engineering Group
  • IP strategy, litigation support, portfolio management, patent prosecution
  • 7918 Jones Branch Drive, McLean, VA 22102
  • Contact: 703-677-3011 | acalderon@rcsc-ip.com

  • Andrew D. Wright, Shareholder
  • Litigation support, portfolio management, patent prosecution
  • 7918 Jones Branch Drive, McLean, VA 22102
  • Contact: 703-677-3012 | awright@rcsc-ip.com

Covington & Burling

  • Melody Wu, Head of Patent Portfolio Counseling
  • IP strategy and litigation
  • One CityCenter, 850 Tenth Street NW, Washington, DC 20001-4956
  • Contact: 202-662-6000 | mwu@cov.com

  • Denise Esposito, Co-Head of Food, Drug and Device Practice
  • FDA navigation
  • One CityCenter, 850 Tenth Street NW, Washington, DC 20001-4956
  • Contact: 202-662-5562 | desposito@cov.com

Latham & Watkins

  • John R. Manthei, Head of Healthcare & Life Sciences Practice
  • FDA navigation
  • 555 Eleventh Street NW, Suite 1000, Washington, DC 20004-1304
  • Contact: 202-637-2211 | john.manthei@lw.com

WilmerHale

Pillsbury

Woods Rogers PLC

*All lawyers listed above have experience in the medical device industry.