Focused Ultrasound Therapy
Focused ultrasound is a rapidly evolving, noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with bone tumors. This novel technology focuses beams of ultrasound energy precisely and accurately on targets deep in the body without damaging surrounding normal tissue.
How it Works
Where the beams converge, focused ultrasound produces precise ablation (thermal destruction of tissue) enabling bone tumors to be treated without surgery. Note: there are some specific bone tumors that have their own entry into our website. For osteoid osteoma, multiple myeloma, sacral chordoma, and bone metastases, please see those separate listings.
The primary options for treatment of bone tumors include invasive surgery.
For certain patients, focused ultrasound could provide a noninvasive alternative to surgery with less risk of complications – such as surgical wound healing or infection – at a lower cost. It can reach the desired target without damaging surrounding tissue and is repeatable, if necessary.
There is a multi-site clinical trial comparing the treatment of osteoid osteoma with magnetic resonance guided focused ultrasound vs. radiofrequency ablation.
There is a pediatric and young adult study underway in Washington, DC that involves the use of FUS in combination with a thermally sensitive form of liposomal doxorubicin on a variety of solid tumors.
There is a clinical trial in Washington, DC, treating osteoid osteoma.
There is a multisite trial in Europe treating patients with bone metastasis comparing focused ultrasound and radiotherapy (FURTHER).
There is a clinical trial in France treating bone metastatic lesions and osteoid osteoma.
There is a clinical trial in Canada treating patients with painful skeletal metastatic lesion with focused ultrasound.
Regulatory Approval and Reimbursement
Bone tumor treatment is approved in Europe, Russia, and China. It is not approved in the United States.
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