Focused Ultrasound Therapy
Focused ultrasound is an early-stage, noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with dystonia. This novel technology focuses beams of ultrasound energy precisely and accurately on targets deep in the brain without damaging surrounding normal tissue.
How it Works
Where the beams converge, focused ultrasound produces precise ablation (thermal destruction of tissue) enabling dystonia to be treated without surgery. While there are several potential treatment targets, the ventrooralis (Vo nucleus of the thalamus) has been the target of initial studies treating musician’s or writer’s dystonia.
The primary options for treatment of dystonia include medications and invasive surgery. However, medications work temporarily, whereas focused ultrasound will offer a more durable treatment that may be permanent.
For certain patients, focused ultrasound could provide a noninvasive alternative to surgery with less risk of complications – such as surgical wound healing or infection – at a lower cost. If needed, focused ultrasound can also be repeated.
A clinical trial in Japan has been completed, and researchers will be publishing the data soon. The trial is aimed at patients who have writer’s cramp or musician’s dystonia of the hand, and studies the safety and initial efficacy for an ablative unilateral Vo thalamotomy. A preliminary report of one patient has been released.
Another clinical trial at Toronto Western Hospital is based on a variety of causes of movement disorders and includes dystonia in the spectrum of diseases for treatment. The purpose is to examine the safety and initial effectiveness of focused ultrasound for treatment of movement disorders. This study is ONLY open to citizens of Canada.
Regulatory Approval and Reimbursement
Focused ultrasound treatment for dystonia is not yet approved by regulatory bodies or covered by medical insurance companies.
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