When using focused ultrasound to create a thalamotomy for essential tremor, does the resulting focal lesion lead to progressive changes in effective connectivity? Do these changes predict clinical outcome? Is it possible to capture direct recordings from stimulated neurons while using focused ultrasound to neuromodulate the brains of large mammals? How does focused ultrasound for gynecological issues fit into the world of minimally invasive and noninvasive medicine? A Special Issue of BJOG: An International Journal of Obstetrics & Gynaecology includes 12 papers that highlight focused ultrasound for the treatment of uterine fibroids, adenomyosis, placenta accreta, endometriosis, and arteriovenous malformation. Other publications address pregnancy outcomes, biomarkers for ovarian reserve, and ablation techniques.

researchroundupHierarchical Dynamic Causal Modeling of Resting-State fMRI Reveals Longitudinal Changes in Effective Connectivity in the Motor System after Thalamotomy for Essential Tremor.
Dr. Jin-Woo Chang at Yonsei University in Seoul, Korea, collaborated with an international group to evaluate changes in effective connectivity after using focused ultrasound thalamotomy to treat patients with essential tremor. See Frontiers in Neurology.

Transcranial Ultrasonic Stimulation Modulates Single-neuron Discharge in Macaques Performing an Antisaccade Task.
Scientists from INSERM, the French National Institute of Health, applied low-intensity transcranial focused ultrasound stimulation while recording real-time neuromodulation in a large animal model. This study demonstrated the researcher’s ability to capture direct recordings from stimulated neurons while applying ultrasound to the brains of large mammals. See Brain Stimulation.

Minimally Invasive and Non-invasive Approaches to the Management of Gynaecological Diseases.
A Special Issue guest edited by Professor Lian Zhang and Professor Rosie Xing, includes 12 papers that highlight focused ultrasound for the treatment of uterine fibroids, adenomyosis, placenta accreta, endometriosis, and arteriovenous malformation. Other publications address pregnancy outcomes, biomarkers for ovarian reserve, and ablation techniques. Wiley has published this supplement with financial support from the International Society for Minimally-invasive and Noninvasive Medicine. See BJOG: An International Journal of Obstetrics & Gynaecology.

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