C. Tempany et al. performed the first clinical trial of uterine fibroids using INSIGHTEC'S Exablate system and found the procedure feasible and safe.

F. Wu et al. performed the first focused ultrasound clinical trial for breast cancer, concluding it could be effective, safe, and feasible in the extracorporeal treatment of localized disease.

Tempany, et al., MR imaging-guided focused ultrasound surgery of uterine leiomyomas. Radiology. Mar 2003;226(3):897-905.

Wu, et al., Randomised clinical trial of high-intensity focused ultrasound ablation for the treatment of patients with localised breast cancer. Br J Cancer. 2003; 15; 89 (12): 2227-33.

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