The University of Oxford has begun a Phase I study investigating heat-activated chemotherapy triggered by focused ultrasound in patients with pancreatic cancer.
The PanDox study uses Celsion Corporation’s ThermoDox® – a proprietary heat-activated liposomal encapsulation of the chemotherapy drug doxorubicin.
Researchers will compare ThermoDox plus focused ultrasound to enhance delivery of the drug in unresectable pancreatic tumors versus systemic delivery of free doxorubicin.
Researchers at Columbia University are seeking patients for a clinical trial using focused ultrasound to facilitate the delivery of chemotherapy to progressive diffuse intrinsic pontine gliomas (DIPGs).
DIPGs are a malignant type of brain tumor that affect children around the age of five.
The study uses a novel neuro-navigational device designed and tested at Columbia.
Watch Now: Two Webinars on Emerging Topics in Focused Ultrasound
Cancer Immunotherapy: Leaders from the Foundation, Cancer Research Institute, and Parker Institute for Cancer Immunotherapy discussed cancer immunotherapy and focused ultrasound’s potential role. WATCH NOW >
Varicose Veins: The Foundation’s FUS Partners Program and Theraclion hosted a webinar on focused ultrasound for the treatment of varicose veins.WATCH NOW >
Dr. Shapiro’s work combines the physical interactions of ultrasound with synthetic biology – the field of science that redesigns organisms for useful purposes.
At Caltech, he leads a 28-person research laboratory dedicated to ultrasound imaging and focused ultrasound.
An international group of neuroscientists investigated the relationship between lesion location and long-term outcome in OCD patients treated with focused ultrasound capsulotomy.
Lesioning an area in the dorsal anterior limb of the internal capsule produced successful, long-term symptom relief.
A new ultrasound pulse sequence can simultaneously evaluate the contributions of thermal and mechanical effects on tissue caused by focused ultrasound.
The sequence uses both thermal strain imaging and harmonic motion imaging.
Several focused ultrasound applications may find this technology useful.
Veterinary researchers at Virginia Tech have written a comprehensive review of using focused ultrasound to treat solid tumor cancers and their metastases.
Treatment techniques discussed include thermal ablation, histotripsy, and the immune effects of focused ultrasound.
The group describes basic principles and suggests future clinical applications in veterinary oncology.
Florida governor Ron DeSantis announced a $12 million funding increase in the state budget for Alzheimer's disease projects, $4.5 million of which is dedicated to focused ultrasound research.
The state will advance research, provide enhanced care and support, and improve and expand diagnostic services.
As part of the investment, SonaCare Medical has merged into a new company called Sonablate Corp.
The company's Sonablate device received FDA clearance in October 2015 for the ablation of prostate tissue, and more than 70 US physicians now offer the treatment.
