Ohio State Joins Alzheimer’s Clinical Trial


The Ohio State University Wexner Medical Center recently announced the start of a clinical trial using focused ultrasound to open the blood-brain barrier in patients with Alzheimer’s disease. The study, NCT 03671889, is also taking place at the West Virginia University School of Medicine and Weill Cornell Medicine.

“Our hypothesis is that by opening the blood-brain barrier, a patient’s own immune defense may clear some of those harmful amyloids,” said neurosurgeon Vibhor Krishna, MBBS. “If we determine this to be safe, in the next steps we would want to understand the effectiveness and the impact of opening the blood-brain barrier in improving cognitive decline.”

Patients who are interested in this study should contact the Center for Neuromodulation at 614-293-2587.

See The Ohio State University’s Press Release >

See The Ohio State University’s Blog: “ Can Focused Ultrasound Help in Fight Against Alzheimer’s?

(Photos and video courtesy of The Ohio State University Wexner Medical Center.)

Related Foundation Coverage:
Profile: Dr. Vibhor Krishna
Potential New Treatment for Epilepsy Using Focused Ultrasound

Media Coverage:
Physics World | Clinical Trial Explores BBB Opening in Fight Against Alzheimer’s 5/8/19
Medgadget | Focused Ultrasound, Guided by MRI, to Treat Alzheimer’s 5/6/19

WKRC12 | Breakthrough Trial on Treating Alzheimer’s Disease Still Accepting Participants 5/6/19