Meeting Report: RSNA 2017


RSNA 2017 Logo with DatesRadiologists from around the world gathered in Chicago from November 26 to December 1, 2017, for the 103rd Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA). The program featured 17 focused ultrasound abstracts and a special session on innovation in Israel that described the spectrum of clinical applications for focused ultrasound technology.

“The range of indications for the focused ultrasound was broad this year, as demonstrated by the large number of clinical and pre-clinical presentations” said Francesco Prada, MD, one of the Foundation’s 2017-2018 Merkin Fellows. “Various groups presented their data on clinical trials for focused ultrasound, which was presented as an established treatment for many different diseases, such as uterine fibroids, prostate cancer, and osteoid osteoma. The range of therapeutic applications encompassed numerous modalities and spanned from focal ablation to hyperthermia and drug delivery with specifically developed carriers. I really enjoyed attending the meeting and met several colleagues who were presenting their data.”

Below is a complete list of the focused ultrasound presentations categorized by indication. To access the full text, go to the meeting website, enter the abstract title in the text box located in the left-hand column, and then click on the title of the presentation.

RSNA 2017 – Focused Ultrasound Topics

Imaging Findings on MR Guided Focused Ultrasound Thalamotomy for Tremor by Ayelet Eran, MD, Alon Sinai, Ilana Schlesinger (Haifa, Israel)

Ultrasound Guided High Intensity Focused Ultrasound Ablation of Breast Fibroadenoma: A Pilot Study by Carrie M. Rochman, MD, George Stukenborg, PhD, Brandi T. Nicholson, MD, Jonathan Nguyen, MD, Jennifer A. Harvey, MD, David Brenin, MD (Charlottesville, VA)

MRI-Guided High Intensity Focused Ultrasound: A New First-Line Technique in the Treatment of Osteoid Osteoma? by Roberto Scipione, MD, Alessandro Napoli, MD, Alberto Bazzocchi, MD, Andrea Leonardi, MD, Susan Dababou, Carlo Catalano, MD (Rome, Italy)

Magnetic Resonance-Guided Focused Ultrasound Surgery for Treatment of Osteoid Osteoma in Pediatric Patients Only: A Multicenter Experience by Francesco Arrigoni, Alessandro Napoli, MD, Alberto Bazzocchi, MD, Simone Quarchioni, Roberto Scipione, MD, Luigi Zugaro, Antonio Barile, MD, Carlo Catalano, MD, Carlo Masciocchi, MD (Rome, Italy)

A Two-Center Phase III, Randomized, Controlled Study of MRgFUS versus EBRT in Patients with Metastatic Bone Disease: Palliative Strategy for Cancer-Induced Bone Pain by Roberto Scipione, MD, Alessandro Napoli, MD, Alberto Bazzocchi, MD, Cristina Marrocchio, Lorenzo Chiurchioni, Carlo Catalano, MD (Rome, Italy)

Non-Invasive MR-Guided Focused Ultrasound Therapy is Associated with Bone Integrity Restoration in Patients with Osteoid Osteoma by Carola Palla, Alessandro Napoli, Fabrizio Andrani, Cristina Marrocchio, Susan Dababou, Carlo Catalano (Rome, Italy)

Liver Cancer
Clinical Results of a Phase I First in Man Study of Targeted Delivery of Lyso-thermosensitive Liposomal Doxorubicin by Extracorporeal Focused-Ultrasound Hyperthermia for Liver Tumours by Paul C. Lyon, BMBS, DPhil, Michael Gray, PhD, BSC, Christophoros Mannaris, PhD, BSC, Robert Goldin, PhD, BMBS, Robert Carlisle, PhD, BSC, Feng Wu, MD, PhD, Mark Middleton, PhD, BmBch, Fergus V. Gleeson, MBBS, Constantin Coussios, PhD (Oxford, UK)

Lung Cancer
Active Targeting Theranostic Iron Oxide Nanoparticles for MRI and Magnetic Resonance-Guided Focused Ultrasound Ablation of Lung Cancer by Na Tang (Shanghai, China)

MR Guided High Intensity Focused Ultrasound (MRgFUS) for the Treatment of Oligometastatic Prostate Cancer Bone Metastasis: Can Soundwaves Downstage Cancer Spread? by Carola Palla, MD, Alessandro Napoli, MD, Cristina Marrocchio, Lorenzo Chiurchioni, Fabrizio Andrani, MD, Carlo Catalano, MD (Rome, Italy)

MR-Guided Focused Ultrasound Treatment for Management of Organ-Confined Intermediate Risk Prostate Cancer: Evaluation of Safety and Effectiveness by Andrea Leonardi, MD, Fabrizio Andrani, MD, Alessandro Napoli, MD, Leonardo Costantino, Valeria Panebianco, MD, Carlo Catalano, MD (Rome, Italy)

Transrectal Contrast-enhanced Ultrasound (CEUS) for Assessment of Ablation Zone after High-intensity Ultrasound (HIFU) for Prostate Cancer by Mittul Gulati, MD, Justin Cheng, MD, Frank K. Chen, MD, Suzanne L. Palmer, MD, Inderbir Gill, MD, Andre L. Abreu, MD (Los Angeles, CA)

Therapeutic Ultrasound Ablation of the Prostate: A Review of Available Devices and Evidence by Karthik Sundaram, Samuel Pevzner, Jason Lane, David Penson, Sandeep Arora (Nashville, TN)

Rectal Cancer
Volumetric Magnetic Resonance-Guided High-Intensity Focused Ultrasound (MR-HIFU) Hyperthermia Combined with Radiation and Chemotherapy for Recurrent Rectal Cancer: Early Phase I Results – William Chu, Oak Brook, IL (POSTER)

Uterine Fibroids or Adenomyosis
Prospective Clinical Trial for Uterine Adenomyosis Using Portable Ultrasound-guided High Intensity Focused Ultrasound: Interim Results by Jae Young Lee, MD, PhD, Hyun Hoon Chung, Maria Lee, Soo Yeon Kang, Keonho Son, Joon Koo Han, MD (Seoul, Korea)

Individual Variables Influencing Clinical Outcome in Women Treated with Magnetic Resonance High-intensity Focused Ultrasound Ablation of Uterine Fibroids (MRgFUS) by Ilaria Capretti, Sonia Iafrate, Ester Cannizzaro, MD, Francesco Arrigoni, Margherita Di Luzio, Aldo Victor Giordano, Sara Mascaretti, Giulio Mascaretti, MD, Carlo Masciocchi, MD ( L’Aquila, Italy)

Clinical Outcome of Uterine Fibroids Treatment: MR Guided High Intensity Focused Ultrasound Compared to Current Therapeutic Strategies by Fabrizio Andrani, MD, Alessandro Napoli, MD, Hans Peter Erasmus, Federica Fanto, Carola Palla, MD, Carlo Catalano, MD (Rome, Italy)

Special Session: Israel Presents: Radiology in Israel— Experience from the Land of Innovation
MRgFUS: spectrum of clinical applications by Yael Inbar (Ramat Gan, Israel)