Key Points
- The 185th Meeting of the Acoustical Society of America (ASA) took place in Sydney, Australia from December 4–8, 2023.
- The program included 29 abstracts that may be of interest to the field.
The 185th Meeting of the Acoustical Society of America (ASA), Acoustics 2023, took place in Sydney, Australia, from December 4–8, 2023.
“The Foundation funded three projects presented at ASA, and I was pleased that data from our multi-institution collaborative immunotherapy project using boiling histotripsy for pancreatic cancer were among those,” said Frédéric Padilla, PhD, the Foundation’s director of the Gene and Cell Therapy Program. “I would also note that one of the Foundation’s Global Scholars, Hadrien Padilla (who is also my son), was on the team from the University of Michigan that presented its transabdominal histotripsy project.”
The program included 29 abstracts that may be of interest to the field. To access the full text of each abstract listed below, search the PDF program for the meeting by abstract number. You may also want to search for your own key terms. Projects marked with the $ symbol were funded by the Foundation.
Abstracts
1aBA1. Optimizing transducer aperture subdivision for aberration correction during transabdominal histotripsy by Ellen Yeats, Hadrien Padilla, Jonathan Sukovich, and Timothy L. Hall from the University of Michigan
1aBA3. Investigation of spatio-temporal inertial cavitation activity for optimization of needle-free ultrasound-enhanced vaccine delivery by Darcy Dunn-Lawless, Joel Balkaran, Brian Lyons, Robert Carlisle, Constantin Coussios, and Michael Gray from the University of Oxford
1aBA4. Investigation of the effect of a multi-frequency ultrasound signal on the inertial cavitation threshold in various viscoelastic mediums by Tatiana Filonets and Maxim Solovchuk from National Taiwan University and the National Health Research Institutes (Taiwan)
1aBA5. Thermal control of engineered induced pluripotent stem cells via focused ultrasound by Kama Bell, Alessandro Howells, Lance Lian, and Jing Yun from Penn State University ($)
1pBA3. Ultra-fast mechanics and bioeffects of acoustic droplet vaporization in tissue-mimicking hydrogels by Mitra Aliabouzar, Bachir A. Abeid, Jonathan B. Estrada, and Mario L. Fabiilli from the University of Michigan ($)
1pBA4. Microfluidic platform using focused ultrasound passing through hydrophobic meshes towards automatic biological experiment by Yusuke Koroyasu, Ruchi Gupta, Tatsuya Yamamoto, Yoichi Ochiai, Nobuhiko Nomura, and Tatsuki Fushimi from the University of Tsukuba (Japan) and the University of Birmingham (UK)
3aBA7. Developing a focused ultrasound treatment for tendinopathies in a large animal model by Grace Wood, Jacob Elliott, and Julianna Simon from Penn State University
3aCA2. Fast and accurate boundary element methods for large-scale computational acoustics. Elwin van ’t Wout, Reza Haqshenas, Pierre Gelat, and Nader Saffari from Pontificia Universidad Catolica de Chile and University College London
3aCA6. Weakly nonlinear ray tracing approximations for focused ultrasound propagation by Matt Foster, Marta Betcke, Ben Cox, and Bradley E. Treeby from University College London
3aPA1. Acoustic cavitation detection in biomedical and underwater systems by Jacob Elliott, Eric Rokni Paul Trzcinski, Michael Krane, Jeff Harris, and Julianna Simon from Penn State University
3aPA2. High-speed observation of bubble and droplet dynamics under irradiation of 1-MHz ultrasound by Nobuki Kudo from Hokkaido University
3aPA3. Bioeffects of microbubbles in tissue engineering: Modeling collapsing jets and microstreaming by Kausik Sarkar from George Washington University
3pBAb5. A mathematical model for maximizing drug uptake in low EPR tumors using different methods of ultrasound-mediated drug delivery by Mohammadaref Ghaderi and Shashank Sirsi from the University of Texas at Dallas
3pBAb7. Focused ultrasound-mediated delivery of anti-programmed cell death-ligand 1 antibody to the brain of a porcine model by Siaka Fadera from Washington University in St Louis
4aBA1. Cavitation in an antivascular cancer therapy setting by David Goertz from the University of Toronto
4aBA2. Cancer ablation with histotripsy by Timothy L. Hall and Zhen Xu from the University of Michigan
4aBA3. Cavitation-enhanced high-intensity focused ultrasound treatment for cancer therapy by Shin-ichiro Umemura, Shin Yoshizawa, Jun Okamoto, and Kazuhito Nemoto from Tohoku University and Sonire Therapeutics
4aBA4. Delivery of ultrasound cavitation therapy with a modified clinical scanner by Lance H. De Koninck, Connor Krolak, Kaleb Vuong, Jeffry Powers, and Mike Averkiou from the University of Washington and Philips Ultrasound
4aPA7. Single focused-beam acoustical tweezers: Trapping cells in 3-D by Zhixiong Gong, Shiyu Li, and Zhichao Ma from Shanghai Jiao Tong University
4pBA1. Real-time cavitation monitoring based on the entropic analysis of ultrasound RF signals by Juan Tu, Renjie Song, Xiasheng Guo, and Dong Zhang from Nanjing University
4pBA2. Active Doppler monitoring of de novo cavitation induced by a dual-mode pulsed high-intensity focused ultrasound array by Randall P. Williams, Minho Song, Yak-Nam Wang, Stephanie Totten, and Tatiana Khokhlova from the University of Washington
4pBA3. Dependence of sonoporation efficiency on microbubble size: An in vitro monodisperse microbubble study by Benjamin van Elburg, Joke Deprez, Martin van den Broek, Stefaan De Smedt, Michel Versluis, Guillaume Lajoinie, Ine Lentacker, and Tim Segers from the University of Twente and the Ghent Research Group on Nanomedicine
4pBA4. Characterization of acute and subacute immune response to boiling histotripsy ablation of pancreatic adenocarcinoma by Tatiana Khokhlova, Yak-Nam Wang, Helena Son, Zhen Xu, Reliza McGinnis, Brett Fite, Aris Kare, Katherine Ferrara, and Frederic Padilla from the University of Washington, the University of Michigan, Stanford University, and the Focused Ultrasound Foundation ($)
4pBA5. Towards in vivo immunotherapy using high intensity focused ultrasound by Guillaume Lajoinie, Yanou Engelen, Karine Breckpot, Dmitri Krysko, Stefaan De Smedt, and Ine Lentacker from the University of Ghent and Vrije Universiteit Brussel
4pBA6. Mechanical disintegration of benign and malignant tumors in ex vivo human prostate tissues using boiling histotripsy by Vera A. Khokhlova, Pavel B. Rosnitskiy, Sergey A. Tsysar, Maria M. Karzova, Sergey V. Buravkov, Natalya V. Danilova, Pavel G. Malkov, Ekaterina Ponomarchuk, Oleg A. Sapozhnikov, Tatiana Khokhlova, Adam D. Maxwell, Yak-Nam Wang, Aleksey V. Kadrev, Andrey L. Chernyaev, and George R. Schade from the University of Washington, Lomonosov Moscow State University, and the Pulmonology Science Research Institute
4pBA7. Inactivation of bacteria using different histotripsy regimes: Toward the treatment of abscesses by Pratik Ambekar, Yak-Nam Wang, Tatiana Khokhlova, Gilles Thomas, Matthew Bruce, Daniel Leotta, Adam D. Maxwell, Pavel Rosnitskii, Stephanie Totten, Jeff Thiel, Shelby Pierson, Keith Chan, Conrad Liles, Evan Dellinger, Adeyinka Adedipe, Wayne Monsky, and Thomas Matula from the University of Washington and Vantage Radiology and Diagnostic Services
4pBA8. Ultrasound-responsive hydrogel microcapsules for on-demand drug release by Rachel D. Field, Margaret A. Jakus, Xiaoyu Chen, Kelia A. Human, Xuanhe Zhao, Parag V. Chitnis, and Samuel K. Sia from Columbia University, Massachusetts Institute of Technology, and George Mason University
4pBA9. Enhancement of brain hyperthermia via transcranial magnetic resonance imaging-guided focused ultrasound and microbubbles — heating mechanism investigation using COMSOL by Zhouyang Xu, Samuel Pichardo, and Bingbing Cheng from Shanghai Tech University and the University of Calgary
5aCA5. High performance calculation of nonlinear wave propagation on GPU for focused ultrasound treatment planning by Maxim Solovchuk from the National Health Research Institutes (Taiwan)
$=Study funded by the Focused Ultrasound Foundation