October 13, 2022 - $2.75 Million Matching Gift for Neurodegenerative Diseases – and more news…

The challenge will help fund our pipeline of projects...
October 13, 2022

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Foundation Receives $2.75 Million Matching Gift to Support Research for Neurodegenerative Disorders
  • The Foundation is funding a pipeline of more than 20 focused ultrasound projects for neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, ALS, dystonia, essential tremor, and Huntington’s disease.
  • The budget for the existing pipeline is $5.5 million, and more projects are planned in the next three years.
  • To help the Foundation reach this goal, a generous donor has issued a matching challenge, committing $2.75 million to be matched 1-for-1.
Foundation News
Watch Now: Webinar on New Approaches with Immunotherapies and Breast Cancer
  • The Foundation and Breast Cancer Alliance recently hosted “New Approaches with Immunotherapies and Breast Cancer.”
  • Learn how emerging immunotherapy research is providing hope to more effectively treat breast cancer.
  • October is Breast Cancer Awareness Month.

Advocacy Partner Highlights Government Bioscience Funding Opportunities
  • The Foundation has partnered with G2G Consulting to provide monthly reports on government bioscience grants – the GBG Report.
  • This effort is part of an ongoing partnership to drive impact for the focused ultrasound community through advocacy.
  • Connect with G2G at the Symposium! Contact Katie Collins.

More Foundation News
Read the Foundation’s 2022 Midyear Report > 
Wellness & Community Outreach Manager, Michelle Majorin, Discusses the Initiatives She Leads at the Foundation [video]
Symposium News
Final Symposium Program Now Available
  • The final program for Symposium 2022 includes dates and times for all proceedings.
  • The interactive template enables users to see the moderators and panelists for each session.

Pfizer’s Senior VP of Gene Therapy and Rare Disease, Bob Smith, Named Keynote Speaker at Symposium 2022
  • Bob Smith is an accomplished biopharmaceutical executive with more than 30 years of experience.
  • He leads Pfizer’s Gene Therapy and Rare Disease portfolio.
  • Mr. Smith will deliver his keynote address at the Symposium on Tuesday, October 25.

Submit Questions Now for FDA Town Hall Session
  • To enable more in-depth answers and critical discussion during the panel, FDA experts encourage Symposium participants to pose their questions in advance of the meeting.
  • The survey link below includes sample questions. 
  • All questions and answers will be posted online ahead of the meeting.

Foundation Experts Now Scheduling Individual Meetings at Symposium
  • Managing director and chief technology officer, Rick Hamilton, is scheduling individual sessions to discuss intellectual property and patent strategy.
  • Senior consultant, Mark Carol, MD, is available to help analyze the costs, payment, and profit for focused ultrasound procedures.

Download the Symposium App
  • The app allows you to view the meeting schedule, create a personal itinerary, connect with other attendees, and see the sponsors and exhibitors.
  • Search “FUSF 2022” in your app store or click the link below to download the free Symposium app.
  • Only Symposium registrants can access the app. Please sign in with the email address you used to register.

Interested in receiving the latest Symposium news? Subscribe now!
Patient News
Male Breast Cancer Virtual Conference Will Include Focused Ultrasound Presentation
  • The Male Breast Cancer Global Alliance Annual Conference will take place October 20 starting at 10:00 am Eastern.
  • David Brenin, MD, FACS, will describe his work using focused ultrasound to treat breast cancer.
  • The event brings together male survivors and supporters for a day of sharing, learning, and camaraderie.
  • Registration is free, but donations are appreciated.

More Patient News
Who is the Ideal Candidate to Receive HIFU? | Urology Times
Dr. Linehan on Her Experience and Learning Curve with HIFU | Urology Times
Exploring High-Intensity Focused Ultrasound as an Organ-Sparing Option for Prostate Cancer | Onc Live
Riverside Health System Now Offering Cutting-Edge Ultrasound Procedure for the Treatment of Essential Tremor and Parkinson’s Disease | Riverside Health System (Virginia)
Research News
Meeting Report: European Association of Neuro-Oncology (EANO) 2022
  • EANO held its 17th Annual Meeting in Vienna September 15–18.
  • Carthera had a prominent presence at the meeting, hosting a lunch symposium and sharing data from its glioblastoma clinical trial.
  • The liquid biopsy consortium meeting included an overview of the ongoing work with focused ultrasound.

New Bibliographic Collection Highlights Focused Ultrasound Immuno-Oncology Publications
  • The Foundation has compiled a publication database that includes almost 100 articles in the field of focused ultrasound immuno-oncology (FUS-IO).
  • This tailored bibliography is now accessible through our Zotero library.
  • The chart at right shows the field’s rapid growth over the past decade.

Cleveland Clinic’s Comprehensive Review of Focused Ultrasound Brain Treatments
  • Researchers at the Cleveland Clinic conducted a comprehensive review of approved and emerging applications of focused ultrasound for treating brain diseases.
  • The article discusses three mechanisms of action and eleven diseases and conditions.
  • Focused ultrasound can deliver acoustic energy through the skull to eliminate defective neurons, introduce drug and biological therapies, and modulate neurons.

Standardization of Focused Ultrasound–Induced Blood-Brain Barrier (BBB) Opening
  • Researchers conducted a systematic review of focused ultrasound parameters used to disrupt the blood-brain barrier (BBB) for drug delivery.
  • The team gathered and collated 107 preclinical and clinical studies, summarized the efficacy and safety findings, and identified gaps and limitations for further study.
  • The group concluded that clinical translation will not become robust until protocols and parameters for BBB disruption have been standardized.

More Research News
MRI-Guided Focused Ultrasound an Effective Tool in the Fight Against Parkinson's Disease | Health Imaging
Industry News
Profound Medical Releases Four-Year Data from Prostate Cancer Clinical Trial
  • New data from the company’s TACT (TULSA-PRO® Ablation Clinical Trial) continue to demonstrate durable and stable safety and efficacy outcomes.
  • The trial enrolled 115 participants with localized prostate cancer and was used to support the device’s FDA clearance.
  • These latest results were presented by Laurence Klotz, MD, at the FOCAL 2022 Conference.

Focused Ultrasound Intellectual Property Update: Third Quarter 2022
  • Five new US patents related to focused ultrasound were issued in the third quarter of 2022.
  • The Foundation tracks recently issued patents and patent applications filed with the US Patent Office related to the field.

'Why It Takes So Long' Blog Series: Reimbursement
  • In the fourth blog in the series, Mark Carol, MD, a senior consultant at the Foundation, gives an overview of the complicated world of reimbursement.
  • The blog post outlines the full reimbursement process from assigning a code to payments and coverage decisions.

More Industry News
Bubbles Have Never Been More Powerful: Histotripsy’s Novel Mechanism of Action in Destroying Targeted Tissues | HistoSonics [video]
Theraclion: New Echotherapy for Varicose Veins Partnership With Parisian Region Hospital Wound Center Announced | Business Wire
Theraclion: The New Strategy Is Paying Off | Business Wire
Profound Medical’s Pro-Talk: Episode 3
  • Thursday, October 20 at 11:00 am Eastern
  • Featuring Mikael Anttinen, MD, Urologist at Turku University Hospital in Finland
  • Geared toward existing and new customers
  • Hosted by Profound Medical

Recent Webinars & Podcasts
New Approaches with Immunotherapies and Breast Cancer | Featuring David R. Brenin, MD, Scott Abrams, PhD, and Michael Nemeth, PhD | Hosted by the Focused Ultrasound Foundation and Breast Cancer Alliance (1 hour 2 minutes)

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Upcoming Events
Call for Abstracts
Today is the last day to submit abstracts for the Society of Interventional Radiology (SIR) Annual Meeting. The meeting will take place in Phoenix, Arizona, March 4–9, 2023.
Visit the Conference Website >​​​​​​

October 13-15, 2022 Veterinary Cancer Society Annual Conference 2022, Norfolk, VA

October 20, 2022 Male Breast Cancer Global Alliance Annual ConferenceVIRTUAL

October 23-27, 2022 8th International Symposium on Focused Ultrasound, Bethesda, MD and VIRTUAL 

November 16-20, 2022 Society for Neuro-Oncology (SNO) Annual Meeting, Tampa Bay, FL

December 5-9, 2022 Acoustical Society of America (ASA) Annual Meeting, Nashville, TN 

December 8-11, 2022 International Symposium on Biomolecular Ultrasound and Sonogenetics (ISBUS), Pasadena, CA 

January 19-23, 2023 Society of Interventional Oncology (SIO) Annual Scientific Meeting, Washington, DC

March 4-9, 2023 Society of Interventional Radiology (SIR) Annual Meeting, Phoenix, AZ 

April 17-20, 2023 22nd Annual International Symposium on Therapeutic Ultrasound (ISTU) and 6th European Symposium on FUS (EUFUS) Joint Conference, Lyon, France​​​​​​