October 13, 2021 - Metastatic Breast Cancer Trial Results Published - and more news

October 13, 2021

Top News | Foundation News | Research News | Industry News | WebinarsEvents
World-First Clinical Trial Demonstrates Focused Ultrasound Can Deliver Antibody Therapy to Breast Cancer Metastases in the Brain
  • Researchers in Toronto published results from this ground-breaking trial today in Science Translational Medicine.
  • Preliminary results indicate that patients experienced a decrease in tumor size of breast cancer metastases in the brain.
  • The study was funded in part by the Foundation.  
Foundation News
Foundation’s Midyear Report Now Available
  • The Foundation and the field of focused ultrasound reached significant milestones in the first half of the year.
  • Highlights of the new report include reimbursement updates, three patient stories, and a spotlight on research and commercialization in Asia.
  • We encourage you to read the report and share it broadly.  

Natasha Sheybani, PhD, Receives NIH Director’s Early Independence Award
  • The award is given to outstanding junior scientists and enables them to launch an independent research career.
  • Dr. Sheybani will be an Assistant Professor in Biomedical Engineering and establish her research laboratory at the University of Virginia this fall.
  • She is also a Senior Scientist at the Foundation.

Workshop Series: Bubble Activity in Therapeutic Ultrasound
  • Speaker details are now available for the next two workshops in the “Detecting, Mapping, and Quantifying Bubble Activity in Therapeutic Ultrasound” virtual series.
  • Registrants can watch previous workshop recordings in the online portal.
  • Join us every Friday until October 29 at 10:00 am Eastern.

Foundation Mourns Loss of Two Friends and Supporters
  • We are sad to report the deaths of two dear friends and Foundation supporters, Albert Small, Sr. and Leigh Middleditch, Jr.
  • Both men were proud to be involved in the Foundation’s efforts to drive progress in the field of focused ultrasound.
Research News
Investigator Update: Nir Lipsman, MD, PhD
  • Dr. Lipsman is the Director of the Harquail Centre for Neuromodulation at Sunnybrook Health Sciences Centre.
  • He leads the recently published trial investigating focused ultrasound for patients with metastatic breast cancer.  
  • This is an update of his original profile from May 2017.  

A New Method for Using Ultrasound Neuromodulation in Deep Regions of the Brain
  • Researchers in Hong Kong completed a study to improve targeting and effectiveness for low-intensity ultrasound neuromodulation of the small animal brain.
  • The group designed and tested a neurostimulation scheme that used gas vesicles to improve spatial resolution.
  • They found the treatment was dose-dependent, repeatable, reversible, and reached a deep-seated region of the brain.

Focused Ultrasound Reduces Pain for Patients with Chronic Knee Osteoarthritis
  • Researchers in Japan recently published clinical trial results using focused ultrasound to treat patients with knee pain secondary to chronic osteoarthritis.
  • The group applied ablative thermal treatment to the site of most severe tenderness around the medial femorotibial joint.
  • Most participants (73.7%) had significant reductions in pain in the 12 months following treatment.

NIH Awards Two Grants for Focused Ultrasound Research
  • Richard Price, PhD, at the University of Virginia received R01 grants from the National Institutes of Health (NIH).
  • The funding will support two projects aimed at increasing the permeability of the blood-brain barrier using focused ultrasound.

Visit our free, online research library of focused ultrasound publications.
More Research News
Feasibility of Magnetic Resonance-Guided High-Intensity Focused Ultrasound Treatment Targeting Distinct Nodular Lesions in Neurofibromatosis Type 1 | DocWire News
Phase 2b Data Point to Safety, Efficacy of Focal Therapy in Intermediate-Risk Prostate Cancer | Urology Times
Sonothermogenetic Pulse Controls Mouse Behavior | Newswise/NIBIB
Merck Preclinical Study Reports 658% Increase in STING Agonist to Tumor When Used in Combination with Vesselon's Drug | PR Newswire
FDA Approves First Trial with Theraclion’s Sonovein Therapy for Varicose Veins in the USA | Venous News
Industry News
Focused Ultrasound Intellectual Property Update: Third Quarter 2021
  • Three new US patents were issued in the third quarter of 2021 related to focused ultrasound.  
  • The Foundation tracks recent patents issued and patent applications filed with the US Patent Office related to the field.

More Industry News
The New Surgery
This short documentary film was created by the team at V.S. Buzaev Memorial International Medical Center for Intelligent Neurosurgery. It addresses neurosurgery without incisions and the opening of the first medical center using focused ultrasound for the treatment of essential tremor and Parkinson's related tremors in Russia.
Nonlinear HIFU: Modeling, Sources, and Bioeffects
  • Thursday, October 28, 2021, at 11:00 am Eastern
  • Presented by Vera A. Khokhlova from the University of Washington
  • Hosted by the International Society for Therapeutic Ultrasound

Detecting, Mapping, and Quantifying Bubble Activity in Therapeutic Ultrasound
  • Every Friday through October 29, 2021, at 10:00 am Eastern
  • Hosted by the Focused Ultrasound Foundation and the American Institute of Ultrasound in Medicine's Future Fund

Do you have news for our newsletter? Tell us about it!
Upcoming Events
October 15-16, 2021 AANS/CNS Tumor Section Satellite Symposium, Austin, TX

November 4-7, 2021 Veterinary Cancer Society Annual ConferenceVIRTUAL MEETING

November 4-7, 2021 DIPG/DMG Collaborative: DIPG Research Symposium, Houston, TX

November 8-11, 2021 Neuroscience 2021 | VIRTUAL MEETING

November 10-14, 2021 Society for ImmunoTherapy of Cancer (SITC) 36th Annual Meeting, Washington, DC and VIRTUAL MEETING

November 18-21, 2021 26th Annual Meeting and Education Day of the Society for Neuro-Oncology (SNO), Boston, MA 

November 28
December 2, 2021 Radiological Society of North America (RSNA) 107th Scientific Assembly and Annual Meeting, Chicago, IL

November 29 
December 3, 2021 Acoustical Society of America (ASA) 181st Meeting, Seattle, WA