May 2018 - International Registry Launches for Pediatric Bone Tumors and More…

May 2018

International Registry Launched to Compare Non-surgical Pediatric Bone Tumor Treatments


Patient story: Jack >
The Hospital for Sick Children (SickKids) in Toronto has launched a multi-center, multi-treatment clinical registry to track and evaluate a range of less invasive treatments for pediatric osteoid osteoma, a benign but painful bone tumor that commonly affects children. Over the next five years, more than 30 international sites will collect outcomes data from 900 children treated for osteoid osteomas with nonsurgical methods – at least 200 of them will have undergone focused ultrasound therapy. 

 Foundation News

Foundation Internship Program Named in Memory of Board Member Charles Steger

Charles Steger, PhD, led one of the longest and most impactful terms as the 15th president of Virginia Polytechnic Institute and State University (Virginia Tech). He joined the Foundation’s Board of Directors in 2016 to “make a difference in improving the human condition.” Dr. Steger died May 6, and we are honored to name the Foundation’s internship program in his memory. 


Watch Now: Data Science In Biomedicine Webinar

Philip Bourne, PhD, Stephenson Chair of Data Science and Director of the Data Science Institute at the University of Virginia, recently led a Foundation webinar exploring data science in biomedicine. He addressed successes and failures thus far, whether or not we are seeing a paradigm shift, and what organizations and researchers can do. The webinar was broadcast via Facebook Live.


FUS Symposium 2018: Important Deadlines Approaching

The 6th International Symposium on Focused Ultrasound is only five months away. Mark your calendar for the important deadlines below, and join us October 21-25 in Reston, Virginia.

June 18 

– Abstract submission closes
– Young Investigator Award applications are due
– Ferenc Jolesz Memorial Award nominations close

September 17
– Early Bird Registration rates end

CNBC Article Addresses Focused Ultrasound’s Clinical and Economic Potential


CNBC's Andrew Zaleski recently reported on the promise of focused ultrasound as a therapy for a range of neurological conditions and the role that device manufacturer Insightec has played in advancing the field. The article also highlighted Koch Disruptive Industries’ multi-million dollar investment in the Israeli company. Foundation chairman, Neal F. Kassell, MD, explained how the field of focused ultrasound has evolved over the past decade.

Read the article: Ultrasound targeting the brain is poised to revolutionize the treatment for Parkinson’s disease >

Foundation Publishes 2018 Spring Report


Progress in the evolution of focused ultrasound to become a standard of care continues to advance, and many milestones have been achieved already this year. We encourage you to read the Foundation's 2018 Spring Report and hope you will share it broadly.  


Reminder: Lockhart Memorial Prize Applications Due July 31


Applications are now being accepted for this annual $75,000 cash award established in memory of Andrew Lockhart. The award is given to an investigator who demonstrates outstanding potential to contribute to advancing cancer treatment using focused ultrasound. In 2017, the prize was awarded to the University of Virginia’s Richard Price, PhD


 Patient News

Ohio State Essential Tremor Patient is “Superhuman”


Bonnie D’Ettore suffered from debilitating tremors for more than 10 years, making everyday tasks like using tape, eating, and signing her name nearly impossible. Her journey is featured on Superhuman, a Freethink original series published on Facebook. The series is intended to inform, challenge, and inspire people to think differently and make a difference. Watch the episode called “Brain Surgery Without Sound” as Bonnie undergoes focused ultrasound therapy at The Ohio State University Wexner Medical Center. 


Millions Learn of Focused Ultrasound Via Popular Primetime TV Program

Focused ultrasound was recently featured on several episodes of the popular hospital drama series, “Grey's Anatomy.” The show, which averages more than eight million viewers per week and airs Thursdays on ABC, included a four-episode storyline in which focused ultrasound treatment was part of an “innovation contest” among doctors to successfully treat a patient with a brain tumor. 


 Research News

Focused Ultrasound Clinical Trial for Depression Begins in Toronto

In a North American first, researchers at Sunnybrook Health Sciences Centre in Toronto have launched a pilot clinical trial to determine the safety, feasibility, and preliminary efficacy of using focused ultrasound to help patients with treatment-resistant major depressive disorder. See our announcement to watch video stories from the first patients treated and find enrollment information for Canadian citizens.  


Investigator Profile: Michael Temple, MD


Michael Temple, MD, is a Canadian interventional radiologist who has performed groundbreaking work using focused ultrasound to treat pediatric patients suffering from osteoid osteomas – benign but painful bone tumors. We spoke with Dr. Temple to learn more about his focused ultrasound work and plans to investigate other pediatric applications.


Focused Ultrasound-Released Brain Tumor Biomarkers Could Replace Biopsy


In a study that has gained the attention of the scientific community and the media, an interdisciplinary group of scientists and clinicians at Washington University in St. Louis have developed a novel procedure to biopsy brain tumors using focused ultrasound.


Theraclion Presents Three-Month Data from Varicose Vein Clinical Trial



Alfred Obermayer, MD, Principal Investigator in Theraclion’s varicose vein study, recently presented the trial’s initial data at the International Vein Congress in Miami, Florida. The research is assessing the feasibility, efficacy, and tolerability of using focused ultrasound to reduce varicose veins. Three-month follow-up data show promising results with no significant side effects.


Foundation Scientists Release Kranion Research Software


The Foundation is pleased to release Kranion®, a highly visual and interactive, open-source transcranial focused ultrasound modeling system for conducting research. The software allows scientists to “see” how the paths of focused ultrasound’s invisible sound waves behave as they pass through a skull. Kranion’s capabilities enable researchers to visualize a proposed treatment plan, model skull geometry, and calculate skull density ratios for patient selection.


Focused Ultrasound Featured in ISMRM Online Education Course

In 2017, Foundation Brain Program Technical Director John Snell, PhD, spoke at the 25th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM) on the history and current neurological applications of focused ultrasound, including a preview of his Kranion treatment modeling software. That presentation is now online as part of ISMRM’s online education program to promote lifelong learning and practice improvement in the magnetic resonance community. Courses are available at basic, intermediate, and advanced levels. 


ISTU 2018 Meeting Summary, Foundation Director Elected to Board


The International Society for Therapeutic Ultrasound (ISTU) recently held its 18th International Symposium for Therapeutic Ultrasound in Nashville, Tennessee. During the symposium, the Foundation’s Director of Extramural Programs, Matt Eames, PhD, was elected to serve a three-year term on ISTU’s Board of Directors. The plenary and educational sessions included numerous focused ultrasound topics with more than 140 presentations specifically related to focused ultrasound. 


Meeting Report: STM 2018



The 35th Annual Meeting of the Society for Thermal Medicine (STM) was held May 7–10 in Tucson, Arizona. The Foundation helped sponsor this international event, which attracted attendees from the fields of engineering, physics, materials science, and biology. The selected focused ultrasound abstracts described two novel preclinical systems, quality assurance methodology, ultrasound beam modeling, and applications for brain, oncology, immunotherapy, and drug delivery.


Research Roundup


Is it possible for genetic therapy to enable long-term treatment of neurological disorders? Can technological advances reduce the time it takes to heal chronic wounds? Has focused ultrasound been accepted into clinical practice for physicians who treat patients with essential tremor? Scientists are asking, and answering, these questions in this month’s research highlights. 


For a full list of this month’s research, visit our free, online research library of focused ultrasound publications.

Tell us about your research news for our next newsletter >
 Industry News

A Closer Look: Koch Disruptive Technologies Leads $150 Million Investment in Insightec


In December, Insightec announced a $150 million Series E funding round led by Koch Disruptive Technologies (KDT), a new subsidiary of Koch Industries focused on finding and funding innovative and emerging companies. The Foundation recently spoke with KDT President Chase Koch, KDT Managing Director Brett Chugg, Insightec CEO and Chairman of the Board Maurice R. Ferré, MD, and Foundation Chairman Neal F. Kassell, MD, about the unprecedented investment and what it means for the future of focused ultrasound.


Focused Ultrasound Achieves Regulatory Milestones in Asia


Two focused ultrasound manufacturers recently announced important regulatory milestones in the Asian market. In China, Profound Medical has gained Food and Drug Administration approval to use Sonalleve® for the treatment of uterine fibroids. In Japan, Insightec is now under pre-market approval from the Pharmaceutical and Medical Devices Agency to use Exablate Neuro to treat mobility, rigidity, or dyskinesia in patients with Parkinson’s disease.


Veterans Health Innovation Challenge Opportunity


A new, open innovation challenge from the Center for Advancing Innovation will launch 20 startup companies focused on creating therapeutics, vaccines, and devices for veteran-related illnesses. The VABeachBio Innovation Challenge is a free, virtual program where participants can earn support from world-class mentors, receive accelerator training and funding, gain media attention from noteworthy outlets, and be considered for best-in-class incubator space.
The deadline to enter is June 15.


Tell us about your industry news for our next newsletter >
 Media Coverage
Neurological News
Veterinary News  Other News
 Upcoming Events
June 1-5, 2018 American Society of Clinical Oncology (ASCO) Annual Meeting, Chicago, IL

June 18-22, 2018 European Society of Paediatric Radiology (ESPR) Annual Meeting, Berlin, Germany

July 17-21, 2018 40th International Conference of the IEEE Engineering in Medicine and Biology Society, Honolulu, HI

July 22-26, 2018 Alzheimer’s Association International Conference, Chicago, IL

July 29-August 2, 2018 American Association of Physicists in Medicine (AAPM) Annual Meeting, Nashville, TN

October 5-6, 2018 12th Interventional MRI Symposium, Boston, MA 
Abstract Deadline is June 1, 2018

October 21-25, 2018 6th International Symposium on Focused Ultrasound, Reston, VA 
Abstract Deadline is June 18, 2018

See the full calendar and submit your event >