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Focus Feature: Focused Ultrasound for Pancreatic Cancer
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- Pancreatic cancer is one of the deadliest and most difficult cancers to detect and treat, underscoring the need for new therapeutic approaches.
- Focused ultrasound can provide thermal or mechanical tissue ablation, mechanical stimulation, drug delivery, and immunomodulatory effects.
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- At least 17 ongoing worldwide clinical trials are testing focused ultrasound for the treatment of pancreatic cancer.
- The studies each take a novel approach and use a variety of clinical systems.
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- Gwangbok Yoo, who runs an architectural technical training institute in South Korea, was diagnosed with pancreatic cancer in 2022.
- After participating in a clinical trial at Seoul National University Hospital, his daily routine has returned to what it was before his diagnosis.
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- Researchers are investigating multiple ways that focused ultrasound could improve pancreatic cancer treatment in laboratory studies.
- Projects include enhancing the delivery of chemotherapy and stimulating the immune system to fight this devastating disease.
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- Meet some of the pioneering clinicians and researchers advancing focused ultrasound for pancreatic cancer around the world.
- Their work spans preclinical discovery, technology development, and clinical trials aimed at improving outcomes for patients.
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- Seoul National University Hospital is a global leader in innovation, research, and clinical care.
- Its focused ultrasound program is led by a multidisciplinary team of radiologists, neurosurgeons, urologists, gynecologists, and biomedical researchers.
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- Foundation workshops convene experts to evaluate the current body of evidence, assess ongoing work, and create a future roadmap.
- A review paper based on the 2024 pancreatic cancer workshop was recently published in Ultrasonography.
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- The Foundation is teaming up with Pancreatic Cancer UK to support preclinical focused ultrasound research.
- Two funded projects, each with a unique approach, are tackling pancreatic tumors.
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- With regulatory approvals already in place in many countries, a wide variety of focused ultrasound companies have entered the pancreatic cancer market.
- Progress is also being made in the United States, with two companies receiving breakthrough device designation.
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“I’m truly grateful that the Foundation made it possible for patients like me to access this advanced technology. I hope many others can benefit from it, too.”
‒ Gwangbok, a pancreatic cancer patient treated in a focused ultrasound trial |
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