December 15, 2022 - Pancreatic Cancer Clinical Trial Results Published and more news…

The data from an initial clinical trial in Korea…
December 15, 2022

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Focused Ultrasound for Pancreatic Cancer: Trial Results Prove Safety, Initial Efficacy
  • The data from an initial clinical trial in Korea were critical for establishing safety, preliminary efficacy, and the protocol parameters for a larger study.
  • Jae Young Lee, MD, PhD, used the ultrasound-guided Alpinion focused ultrasound device plus standard-of-care chemotherapy to decrease tumor size in patients with pancreatic cancer.
  • A phase II clinical trial is now underway in Korea and nearing its enrollment goal.

Liver Tumor Patient Participates in Focused Ultrasound Histotripsy Clinical Trial
  • Peter's neuroendocrine cancer has caused tumors throughout his body, including his liver.
  • He took part in a focused ultrasound clinical trial in the UK that is exploring histotripsy to noninvasively destroy liver tumors.
  • The cancer is stable, so researchers will monitor Peter to see whether the histotripsy triggers an immune response.
  • The #HOPE4LIVER trial is being sponsored in the US and Europe by HistoSonics.
Foundation News
Visiting Scholars Work to Accelerate the Field of Focused Ultrasound
  • This fall, an intern and a visiting scholar joined the Foundation and took different approaches toward the same goal of advancing the field of focused ultrasound.
  • Visiting scholar Yi-Hsiu Chen gained preclinical and clinical research experience that will help further the focused ultrasound program at her hospital in Taiwan.
  • Fall intern Imogen Hequet explored machine learning and its intersection with focused ultrasound.

In Memoriam: Rick Frisbie
  • The Foundation is saddened to share that a longtime supporter, Rick Frisbie, passed away last month.
  • We are grateful to Mr. Frisbie and his wife Barbara for helping to advance the Foundation’s mission as donors, advocates, and as a patient.
Patient News
Toronto Hospital Marks 300 Focused Ultrasound Treatments for Essential Tremor
  • Sunnybrook Health Sciences Centre recently announced that it had reached an important treatment milestone.
  • Chris Smith was the 300th patient to receive focused ultrasound for essential tremor at Sunnybrook.
  • After the procedure, Smith noted the “shocking difference” in his tremor, saying “My left side tremor had not only diminished, but entirely disappeared!”

More Patient News
With More Treatment Options, Outcomes Improve for Patients with Epilepsy | EurekAlert!
Dr. David Silver Discusses His Experience with HIFU | Urology Times [video]
Health Beat: Focused Ultrasound to Treat Parkinson's | WFMZ TV Allentown, PA [video]
Research News

Watch Now: Webinar on How to Access Grant Funding
  • The Foundation and G2G Consulting partnered to host a webinar on current federal funding opportunities and tips for securing research funding.

Biomedical Technology Prize to Recognize Innovators Impacting Health
  • The Richard N. Merkin Prize in Biomedical Technology will recognize scientists who have developed technologies that substantially impact human health.
  • Up to four awards will be given annually, and recipients will share a $400,000 prize.
  • Dr. Merkin has advanced biomedical research that improves lives and is a longtime Foundation supporter.
  • Nominate a colleague now through January 30.

Research Awards Seek Projects that “Make it Better” for Osteosarcoma Patients
  • Make it Better (MIB) Agents is seeking applications for “Outsmarting Osteosarcoma” research prizes.
  • Two awards are available – one for researchers and one for young investigators – for studies that address osteosarcoma.
  • Applications are due February 3, 2023.

More Research News
Ultrasound Shows Potential in Treating Alzheimer’s, Says WVU Study | WBOY Clarksburg, WV
Study: Focused Ultrasound Shows Promising Potential for Future Alzheimer’s Treatment | West Virginia University
Industry News
‘Why It Takes So Long’ Blog Series: Physicians
  • In this fifth blog in the series, Mark Carol, MD, a senior consultant at the Foundation, addresses the challenges in asking physicians to adopt a new medical technology
  • Some of the hurdles discussed in the blog include payment discrepancies, turf battles, and education.

EDAP to Begin Endometriosis Clinical Trial
  • EDAP TMS has been granted regulatory approval in France to initiate a clinical trial evaluating HIFU as a potential treatment for rectal deep infiltrating endometriosis.
  • The trial will use the company’s Focal One device and enroll 60 patients.
  • Patient enrollment is planned to begin in the spring of 2023.

Sonablate Corp. Partners with Agiliti to Increase Patient Accessibility
  • Sonablate Corp. has announced a three-year agreement with Agiliti to more widely deploy Sonablate HIFU devices.
  • Agiliti helps more than 9,000 healthcare customers in the US access and mobilize medical devices to reduce costs and optimize patient outcomes.

HistoSonics Announces $100 Million in Financings
  • Proceeds of the financings will be used to support the company’s commercial launch and clinical trials.
  • HistoSonics also plans to expand the applications of its novel histotripsy therapy platform throughout the body.
  • The press release includes an addition to the company’s Board of Directors: Erica Rogers, President and CEO of Silk Road Medical, Inc.

More Industry News
Non-Invasive Brain Disease Treatment Center Established in Shanghai | Shine

Recent Webinars & Podcasts
How to Access Grant Funding | Hosted by G2G Consulting and the Focused Ultrasound Foundation (59 minutes)
Acoustic Cluster Therapy (ACT®) Increases Blood-Brain Barrier Permeability and Enhances Accumulation of Nanoparticles in Brain Tissue | Featuring Catharina de Lange Davies, Professor of Physics, Norwegian University of Science and Technology | Hosted by the International Society for Therapeutic Ultrasound (58 minutes)

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Upcoming Events
January 19-23, 2023 Society of Interventional Oncology (SIO) Annual Scientific Meeting, Washington, DC

March 4-9, 2023 Society of Interventional Radiology (SIR) Annual Meeting, Phoenix, AZ 

March 19-24, 2023 Winter School on Therapeutic Ultrasound, Les Houches, France | ​​​​​Registration is now open!​​​​​​

April 17-20, 2023 22nd Annual International Symposium on Therapeutic Ultrasound (ISTU) and 6th European Symposium on FUS (EUFUS) Joint Conference, Lyon, France | ​​​​​Abstracts are due today, December 15. ​​​​​​

April 23-27, 2023 38th Annual Society for Thermal Medicine (STM) Meeting, San Diego, CA | Abstracts are due December 31. ​​​​​​