August 20, 2026 – Focus Feature: 2026 State of the Field Report…

The Foundation recently released the latest State of the Field Report, which documents the extraordinary progress in the field of focused ultrasound over the past year (2025). Highlights include new regulatory approvals, a record amount invested in the field, and an overview of commercial treatment sites worldwide.

The State of the Field data are available in two formats:

The interactive platform features in-depth statistics on the field of focused ultrasound that are updated regularly throughout the year. This platform enables a richer, more flexible experience where users can drill down into the data and explore by interest, including indications, sites, approvals, coverage, manufacturers, and more.

The PDF report is released once a year and provides a point-in-time snapshot of the field with historical context and long-term trend analysis.

We encourage you to read on for key highlights from this year’s report.

In 2025, more than 74,800 patients were treated using nearly 2,000 commercial devices installed worldwide. Of those, 226 devices were installed in the past year. There were 19 new unique regulatory authorizations, bringing the total to 451 worldwide. Across the industry, both investments and the number of companies saw significant growth.

In 2025, researchers identified 18 new indications where focused ultrasound could make a difference, bringing the total to 196. Of those, 12 indications progressed to first-in-human clinical trials.

The video below shows how the field has grown and changed countless lives. Watch Now.

In 2025, nearly 75,000 patients were treated with focused ultrasound, bringing the cumulative total to 1,093,642. Women's health indications, such as uterine fibroids and adenomyosis, account for the largest share of focused ultrasound procedures performed to date. Urological indications, including prostate tumors, BPH, and kidney tumors, make up the second-largest treatment area.

Neurological applications follow closely behind. To date, there have been 27,563 focused ultrasound treatments for essential tremor, making up 81% of all neurological treatments. Learn more.

Before a focused ultrasound procedure can be introduced into clinical practice, the device must first receive authorization from the appropriate governing body. Last year, there were 19 new regulatory authorizations for focused ultrasound worldwide granted by 8 different bodies. These decisions authorized the commercial use of devices from six focused ultrasound companies. In total, the field has amassed 451 authorizations from 45 regulatory agencies. Learn more.

As insurance coverage expands, financial barriers are reduced for patients, providers gain a sustainable pathway for offering treatment, and access to care increases. As of the end of 2025, 18 countries offer some level of reimbursement for 19 indications worldwide and 8 in the US. Meanwhile, essential tremor, tremor-dominant Parkinson’s disease, prostate tumors, and bone metastases lead the list of lives covered in the US. Learn more.

Clinical research continued to expand in 2025, with 73 new research sites established worldwide for a total of 391. The United States and China accounted for the largest shares of this new activity. Nearly 100 indications are currently being investigated in clinical trials globally. Learn more.

Last year was a strong year for the industry with more than 225 new focused ultrasound devices installed worldwide, bringing the total number to nearly 2,000. The number of focused ultrasound companies increased 27% to 152, while the median number of employees per company fell from 21 to 13. These figures indicate that many of the new companies are early stage. Learn more.

Last year, 25 focused ultrasound companies raised approximately $628 million, making it one of the strongest years on record for the sector. Notably, about half of the 2025 transactions occurred at the earliest stages of company formation and growth, with 13 financings classified as Series A or earlier. Cumulatively, more than $3.5 billion has been invested in the field. Also, despite concerns surrounding federal research funding and widely publicized efforts to reduce government spending, funding for focused ultrasound research increased by approximately $10 million in 2025. Learn more.

Note: The data presented in the State of the Field PDF and interactive version are based on self-reported information from manufacturers that voluntarily participated in our annual survey. The figures are accurate to the best of the Foundation’s knowledge.