April 21, 2022 - A Potential Therapy for Diabetes - and more news



April 21, 2022

Top News | Foundation News | Symposium News 
Research News | Industry NewsWebinarsEvents

Focused Ultrasound: A Potential Non-Drug Therapy for Diabetes
  • A large, multicenter team of researchers partnered with GE Research to study the use of focused ultrasound for the treatment of diabetes.
  • Focused ultrasound neuromodulation could be used to prevent or reverse Type 2 diabetes.
  • The results of the preclinical study were published in Nature Biomedical Engineering.
Foundation News
Stefan Vilsmeier Joins Foundation’s Council
  • Vilsmeier is founder and CEO of Brainlab, a global medical software and hardware company improving access to and consistency of medical treatments.  
  • The Council is a dedicated group who provide advice and assist with raising funds and building awareness.

Register Now: Webinar on Aging and Longevity
  • Age Wave Founder and CEO, Ken Dychtwald, PhD, will address rising longevity and the important role that disruptive medical technology plays to this generation and beyond.
  • Join us Tuesday, May 10, at 1:00 pm Eastern.  

Three Days Left to Apply for 2022 Summer Global Internships
  • The Foundation’s Global Internship Program funds students who are interested in focused ultrasound to conduct research with mentors in the field.
  • Applications for this three-month summer research experience will be accepted through midnight Eastern on April 24.

Advocacy Update: Voice Your Support for Focused Ultrasound Funding
  • The Foundation and our partners at MITA are asking Congress to dedicate funding for focused ultrasound research.
  • Please write to your member of Congress to express your support.
  • We provide messaging guidelines and instructions.
Symposium News
Gail ter Haar, DSc, Receives Foundation’s 2022 Visionary Award
  • Professor Gail ter Haar, an expert in focused ultrasound and physics, is the recipient of this year’s Visionary Award.
  • She leads the therapeutic ultrasound team at The Institute for Cancer Research and is founding President of the International Society for Therapeutic Ultrasound.
  • At the meeting, she will address the future of therapeutic ultrasound and lessons to be learned from the past.

Submit Your Nominations for the Ferenc Jolesz Memorial Award
  • The award honors the late Ferenc Jolesz and recognizes an innovative spirit in a mid-career investigator conducting focused ultrasound research.
  • The recipient will receive a $5,000 cash award and up to $5,000 in travel expenses for Symposium attendance.
  • The award is supported by Insightec, and nominations will be accepted through Monday, June 6.

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Research News
Improving Focused Ultrasound Blood-Brain Barrier Opening
  • Researchers sought to improve how focused ultrasound is used to open the blood-brain barrier (BBB) in preclinical studies.
  • The group synthesized and analyzed two protein binders that weaken the BBB before applying ultrasound energy.
  • Pretreatment incubation of tight junction proteins with clinically suitable binders may improve BBB opening and increase the therapeutic window.

Sonodynamic Therapy Review Article Published in Cancer Letters
  • Sonodynamic therapy (SDT) uses focused ultrasound to activate agents that accumulate in tumor cells and cause cell death.
  • A recent comprehensive review discusses SDT for primary and metastatic tumors, the agents used, combination therapies, and proposed cellular mechanisms.

NIH’s Research Initiatives Secure Increased Funding
  • Congress recently passed a bill that includes $620 million for the NIH BRAIN Initiative – $60 million more than in 2021.
  • The bill also secured funding for the NIH HEAL Initiative, which aims to end addiction.
  • BRAIN and HEAL are currently funding multiple focused ultrasound research projects.

More Research News
Long-Term Outcomes of Whole Gland High-Intensity Focused Ultrasound for Localized Prostate Cancer | Physician’s Weekly
Study Shows SonoCloud Ultrasound Technology Is Safe for Alzheimer’s Patients | MDDI Online
Ultrasound Gave Us Our First Baby Pictures. Can It Also Help the Blind See? | USC Viterbi School of Engineering
Outcomes of Partial Gland Ablation Using High Intensity Focused Ultrasound for Prostate Cancer | GU Oncology Now
Industry News
Company Profile: Alpinion Medical Systems
  • Alpinion Medical Systems is a Korea-based focused ultrasound manufacturer with offices in the US, Germany, and China.
  • The company's Alpius HIFU device is used to treat uterine fibroids and adenomyosis, and clinical trials are underway for pancreatic cancer.
  • Alpinion also designs, manufactures, and sells ultrasound imaging systems and six types of ultrasound transducers.

Cost Comparison Between Standard-of-Care and Focused Ultrasound Therapies
  • The profitability of focused ultrasound treatments is a critical decision point for those who are investing in devices for their treatment sites.
  • The Foundation has developed a tool to compare the cost of focused ultrasound to other standard-of-care therapies.
  • The tool is available to industry to assist in selling focused ultrasound technology to prospective customers and help guide future commercial endeavors.

Microvascular Therapeutics Receives Funding to Develop Ultrasound Contrast Agent
  • Microvascular Therapeutics, based in Tucson, AZ, is developing a new ultrasound contrast agent, MVT-100.
  • They received a Commercialization Readiness Program grant from the National Heart, Lung, and Blood Institute.
  • The company plans to enhance quality control systems, optimize production, and conduct market research.
Decades with PD: “Ask Me Anything!”
  • April 27 at 7:00 pm Eastern
  • Featuring Dr. Alice Lazzarini and three patients with Parkinson’s disease
  • Hosted by Rebecca Gilbert, MD, PhD, of the American Parkinson’s Disease Association

Delivering Drugs to the Brain
  • April 28 at 10:00 am Eastern
  • Featuring Zhenpeng Qin, PhD, Olaf van Tellingen, PhD, Costas Arvanitis, PhD, and Graeme F. Woodworth, MD
  • Hosted by Drug Discovery News

Sonobactericide for Treating Bacterial Infections
  • April 28 at 11:00 am Eastern
  • Featuring Klazina Kooiman, PhD, from Erasmus MC University Medical Center Rotterdam
  • Hosted by the International Society for Therapeutic Ultrasound

Recent Webinars & Podcasts
IPMDS Podcast: Bilateral Focused Ultrasound Thalamotomy for Essential Tremor, Is It Safe? | Featuring Prof. Andreas Lozano from the University of Toronto (12 minutes)
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Upcoming Events
April 21, 2022 32nd Annual Pediatric Neurology Update: The Future of Neuroscience 2022, Children's National Hospital, Washington, DC 

April 28, 2022 Virginia Bio THRiVE, Roanoke, VA

May 1, 2022 Breast Cancer Alliance 5K + Wellness Weekend, Greenwich, CT

May 1-4, 2022 Society for Thermal Medicine (STM) 2022 Annual Meeting | VIRTUAL EVENT 

May 3, 2022 National Brain Tumor Society Head to the Hill 2022 | VIRTUAL EVENT 

May 7-12, 2022 International Society for Magnetic Resonance In Medicine (ISMRM) Annual Meeting 2022, London, UK

May 23-27, 2022 182nd Acoustical Society of America (ASA) Meeting, Denver, CO

June 7-10, 2022 21st Annual International Symposium on Therapeutic Ultrasound (ISTU), Toronto, Canada and VIRTUAL

June 11-16, 2022 Society of Interventional Radiology (SIR) Annual Meeting, Boston, MA

June 19-23, 2022 15th International Stereotactic Radiosurgery Society (ISRS) Congress, Milan, Italy

July 10-14, 2022 American Association of Physicists in Medicine (AAPM) Annual Meeting, Washington, DC

August 14-19, 2022 Gordon Research Conference – In Vivo Ultrasound Imaging, Ventura, CA

October 10-13, 2022 IEEE International Ultrasonics Symposium, Venice, Italy

October 23-28, 2022 8th International Symposium on Focused Ultrasound, Bethesda, MD

December 8-11, 2022 International Symposium on Biomolecular Ultrasound and Sonogenetics (ISBUS), Pasadena, CA