Meeting Report: Pan Canada Neurotechnology Ethics Collaborative
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“From Talk to Action: Canadian Leadership Ethics and Neurotechnology” was the theme of the Pan Canada Neurotechnology Ethics Collaborative’s virtual workshop held June 8, 2020.
Master’s Student Completes Foundation-funded Thermometry Project
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One of the Foundation’s central values is to foster the next generation of researchers, and we are proud to announce that Yekaterina “Katya” Gilbo recently completed her work on a focused ultrasound thermometry project sponsored by the Foundation and earned her Master of Science degree in Biomedical Engineering from the University of Virginia.
Call for Comments: Guidelines for Immune Analysis During Focused Ultrasound Research
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Focused ultrasound is an early-stage, noninvasive therapeutic technology with the potential to improve the lives of patients with cancer by providing either an alternative or complement to existing therapies. A growing body of research has demonstrated that focused ultrasound can initiate a powerful anti-tumor immune response that complements other immunotherapies, such as checkpoint inhibitors. This combination approach has the potential to enhance the effectiveness and reduce the side effects of current immunotherapy treatments. Currently, the first clinical trials pairing focused ultrasound with immunotherapy drugs are underway, investigating this combination approach in patients with advanced metastatic cancers.
In July 2019, the Foundation partnered with the Cancer Research Institute to host a Focused Ultrasound and Cancer Immunotherapy Workshop. That meeting culminated in a clear roadmap of important projects and next steps for the field. The group determined that the highest priority was the need to develop guidelines for immune analysis during focused ultrasound studies, including protocols for optimal collection and storage of tissue samples and prioritized immune assays. As the field continues to grow, it is critical that all studies use the same methods of analysis whenever possible so results can be compared as researchers examine the effects of varying drug combinations in multiple tumor models.
In recent months, the Foundation has drafted guidelines – for preclinical and clinical studies – with the input of our Cancer Immunotherapy Scientific Advisory Board and several other researchers in this field. We are pleased to invite public comment on these documents.
The proposed guidelines include suggestions for analysis decision trees and assays. We emphasize the need to run a few, very pointed assays/analyses first, before storing remaining samples for later analysis.
We encourage the community to review these preclinical and clinical guidelines and submit comments until August 1, 2020.
See “Guidelines for Immune Analysis Following FUS Treatment – Preclinical” >
See “Guidelines for Immune Analysis Following FUS Treatment – Clinical” >
Submit your Comments >
Focused Ultrasound—Assisted Liquid Biopsy in the Brain
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