A team at the University of Virginia (UVA) has joined a multicenter clinical trial evaluating the safety of using focused ultrasound to enhance the delivery of chemotherapy in patients with glioblastomas (GBM).

Elisa Konofagou, PhD, the Robert and Margaret Hariri Professor of Biomedical Engineering and Radiology at Columbia University, and her research team recently treated the first patient in their clinical trial to open the blood-brain barrier (BBB) in patients with Alzheimer’s disease.

A collaborative group of researchers in the US has now published the results from their pilot study showing focused ultrasound to be a safe and feasible treatment for the motor fluctuations and dyskinesias from Parkinson’s disease (PD). Notably, this was the first study where The Michael J. Fox Foundation for Parkinson’s Research participated in funding focused ultrasound treatment.

Brain Clinical Project: Cervical Dystonia Clinical Trial
The Foundation’s Brain Clinical Program has selected a new project to fund in the fourth quarter of 2020. Shiro Horisawa, MD, will use focused ultrasound to treat patients with cervical dystonia, a painful condition in which neck muscles contract uncontrollably. There is currently no cure for this debilitating condition.

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