Highlights include:
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Brigham and Women’s Hospital — Seung-Schik Yoo, Nathan McDannold, and Natalia Vykhodtseva have arguably the most advanced preclinical studies in their respective areas. Dr. Yoo’s recent Neuroreport publication found a longer time delay associated with FUS-mediated motor response, suggesting nonelectrical neuromodulation (a distinctive brain stimulation method). |
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Institut Langevin, France — Jean-Francois Aubry and his group in Paris recently published results showing their work studying the effects of pressure and anesthesia while using FUS to induce neuromodulation. |
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Sheba Medical Center, Israel — Besides studying other forms of neuromodulation and indications for neuromodulation, Sagi Harnof reports repeatable success with FUS neuromodulation in a preclinical model. The Sheba group is studying pain treatment for patients with end-stage cancer and has plans to study several other brain diseases. |
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Stanford University — Kim Butts-Pauly and her team are studying both acoustic radiation force imaging (ARFI) simulation and the way that neuromodulation affects neuronal firing. Using them together, they are developing a clinical use scenario to first verify a focal spot with ARFI, then confirm it with neuromodulation, and finally create a permanent lesion with ablation. |
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The Technion, Israel — Eitan Kimmel, Shy Shoham, and their colleagues are discovering the exact way that neuromodulation affects the cellular membranes of neurons and have published their new model to describe the phenomenon. |
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The University of Utah — Jeff Anderson and his group at Utah are studying neuromodulation for brain mapping and the use of diagnostic neuromodulation to help patients who suffer brain damage while breathing on a ventilator. They are looking for biomarkers that may indicate that damage is about to occur or biomarkers that identify certain disorders. |
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The U.S. Food and Drug Administration — Matthew Myers and his group are interested in the potential of FUS-induced neuromodulation to study the effects of blast-induced traumatic brain injury (TBI). They are looking for cures to treat the effects of TBI, including disruption of the blood-brain barrier, inflammation, immune responses, behavioral disturbances, and sleep disorders. |