At this year’s meeting of the Society for Thermal Medicine, there was a special session on the use of focused ultrasound for hyperthermia, which is being used to enhance the delivery of anticancer drugs and the efficacy of other therapies like radiation. Hyperthermia to induce an anticancer immune response was also a hot topic this year, with two sessions devoted to immune-based treatments. Novel nanoparticle-based combination therapies and veterinary applications for hyperthermia further emphasized the broad range of uses for this exciting technology.

Abstracts Presented

STM meeting logo 2017Histological evaluation of cellular changes in healthy bone after MRI guided High-Intensity Focused Ultrasound: an acute and chronic study in pigs
Karolina Piorkowska*1, Gino R. Somers2,3, James Drake1,4, Adam C Waspe1,5
1Centre for Image Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Canada, 2Department of Pathology, The Hospital for Sick Children, Canada, 3Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada, 4Department of Neurosurgery, The Hospital for Sick Children, Canada, 5Department of Medical Imaging, University of Toronto, Canada
Sunday, April 30th: Biology Session II: Mechanisms and Agents of Cell Stress to Enhance Therapy - 4:00pm-6:00pm

Real-time Spatiotemporal Control of Transcranial Focused Ultrasound In Vivo
Dalong Liu1,2, Kyle Schaible1, Walter Low1, Emad Ebbini*1
1University of Minnesota Twin Cities, USA, 2Siemens Health Solutions, USA
Tuesday, May 2nd: Physics Session III - Therapeutic Opportunities with Ultrasound and other Energy Sources - 9:30am-11:30am

Targetability of Adult Soft Tissue Sarcomas for Mild Hyperthermia Treatments Using Magnetic Resonance Imaging-guided High-Intensity Focused Ultrasound
Jochen Cammin*1, Satya V.V.N. Kothapalli2, Hong Chen2, Ari Partanen3, Imran Zoberi1, Michael B. Altman1
1Washington University in St. Louis, Department of Radiation Oncology, USA, 2Washington University in St. Louis, Department of Biomedical Engineering, USA, 3Philips, Clinical Science MR Therapy, USA
Monday, May 1st: Clinical Hyperthermia Session II - New Opportunities for Oncology - 9:30am-11:30am

Effect of hyperthermia duration on MR-HIFU mediated doxorubicin delivery from thermosensitive liposomes: In vivo biodistribution and comparison with numerical models
Robert Staruch1,2, Sumbul Shaikh1, Chenchen Bing1, Joris Nofiele1, Debra Szczepanski1, Yu Hong1, Michelle Wodzak1, Dieter Haemmerich3, Noelle Williams1, Theodore Laetsch*1,4, Rajiv Chopra1
1UT Southwestern Medical Center, USA, 2Philips Research, USA, 3Medical University of South Carolina, USA, 4Children's Health, USA
Tuesday, May 2nd: Nanotechnology Session IV - In vivo Preclinical Models of Magnetic Hyperthermia - 9:30am-11:30am

Identification of clinical MR-HIFU hyperthermia treatment sites through validation of MR thermometry accuracy and precision in healthy volunteers
Satya V.V.N. Kothapalli*1, Michael B. Altman2, Ari Partanen3, Lifei Zhu1, Galen Cheng1, H. Michael Gach2, Imran Zoberi2, Dennis Hallahan2, William Straube2, Hong Chen1,2
1Department of Biomedical Engineering, Washington University in St. Louis, USA, 2Department of Radiation Oncology, Washington University in St. Louis, USA, 3Clinical Science MR Therapy, Philips, USA
Sunday, April 30th: Physics Session I: Efforts to improve QA for clinical hyperthermia - 9:30am-11:30am

Modeling and Measurement of Heating Patterns of a HIFU Applicator: preliminary results
Raquel Martinez*1, A. Ramos2, A. Vera3, L. Leija3
1Department of Biomedical Engineering, Polytechnic University of Chiapas, Mexico, 2Group of R&D “Systems and Ultrasonic Technologies”, Institute for Physical and Information Technologies, CSIC, Spain, 3Electrical Engineering Department, Bioelectronics Section, CINVESTAV-IPN, Mexico
Sunday, April 30th: Poster Session & Competition - 6:00pm-8:00pm

MR-guided HIFU-induced hyperthermia for local drug delivery in breast cancer: MR thermometry evaluation and preclinical validation
Roel Deckers*1, Charles Mougenot1, Josanne S. De Maar1, Manon N.G. Braat1, Britt B.M. Suelmann2, Sabine C. Linn3, Elsken Van der Wall2, Clemens Bos1, Lambertus W. Bartels1, Chrit T.W. Moonen1
1Imaging Division, University Medical Center Utrecht, The Netherlands, 2Cancer Center, University Medical Center Utrecht, The Netherlands, 3Pathology, University Medical Center Utrecht, The Netherlands
Tuesday, May 2nd: Physics Session III - Therapeutic Opportunities with Ultrasound and other Energy Sources - 9:30am-11:30am

Phase I trial of MR-HIFU mild hyperthermia with radiation and chemotherapy for recurrent rectal cancer: second patient
William Chu*1,3, Samuel Pichardo5,6, Yuexi Huang1,2, Robert Staruch4, Ari Partanen5, Merrylee McGuffin1, Gregory Czarnota1,2, Kullervo Hynynen2,3
1Sunnybrook Health Sciences Centre, Canada, 2Sunnybrook Research Institute, Canada, 3University of Toronto, Canada, 4Philips Research, USA, 5Philips Healthcare, USA, 6Thunder Bay Regional Research Institute, Canada, 7Lakehead University, Canada
Monday, May 1st: Clinical Hyperthermia Session III - Case Studies and Non-oncology Applications - 1:30pm-3:00pm

Tissue Fractionation using Microsecond-Long HIFU Pulses on a Clinical MR-HIFU System
Avinash Eranki*1,2, Navid Farr2, Ari Partanen3, Karun V.Sharma1, Christoper T.Rossi1, AeRang Kim1, David Woods2, Pavel Yarmolenko1, Peter C.W.Kim1, Bradford J.Wood2
1Childrens National Health System, USA, 2National Institutes of Health, USA, 3Philips, USA
Sunday, April 30th: Poster Session & Competition - 6:00pm-8:00pm

Effect of hyperthermia duration on MR-HIFU mediated doxorubicin delivery from thermosensitive liposomes: In vivo biodistribution and comparison with numerical models
Robert Staruch1,2, Sumbul Shaikh1, Chenchen Bing1, Joris Nofiele1, Debra Szczepanski1, Yu Hong1, Michelle Wodzak1, Dieter Haemmerich3, Noelle Williams1, Theodore Laetsch*1,4, Rajiv Chopra1
1UT Southwestern Medical Center, USA, 2Philips Research, USA, 3Medical University of South Carolina, USA, 4Children's Health, USA
Tuesday, May 2nd: Nanotechnology Session IV - In vivo Preclinical Models of Magnetic Hyperthermia - 9:30am-11:30am

See the 2017 STM Meeting Website >

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