The 105th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA) took place December 1-6 in Chicago. The conference’s 50,000 attendees included interventional radiologists, diagnostic radiologists, researchers, and allied professionals who attended more than 400 sessions to gain hands-on experience with cutting-edge technology and the latest advances in the field.



RSNA 2019Along with “Value MR Imaging-Paradigm Shift from Generic to Targeted–Why and How,” a special interest session led by Clare Tempany-Afdhal, MB, BAO, BCh, the program featured 26 focused ultrasound abstracts (12 more than last year) covering brain, central nervous system, bone, cancer, women’s health, prostate, and thyroid applications.

“Our value-MR imaging-Paradigm shift from generic to targeted-why and How session garnered much interest and lively discussion,” said Dr. Tempany, Ferenc Jolesz, MD, Professor of Radiology at Harvard Medical School and Vice Chair of Research in the Department of Radiology at Brigham and Women’s Hospital. She spoke on MR guided FUS is there value in disruption. “Focused ultrasound is being very well received this year with many applications reaching maturity and now clearly demonstrable valuable additions to patient care. Perhaps even more exciting, there were multiple new applications at this year’s meeting, such as Alzheimer’s disease, pancreatic cancer and thyroid nodules.”

Below is a complete list of the focused ultrasound presentations categorized by indication. To access the full text, click on the title of the presentation.

Brain and Central Nervous System (8)

Quantification of Blood Spinal Cord Barrier Opening After Application of Magnetic Resonance Guided Focused Ultrasound. Cross C, Payne A, Hawryluk G, Haag-Roeger R, Cheeniyil R, Odeen H, Minoshima S, Cross D, Anzai Y.

Mapping the Cortical Connections of the Ventral Intermediate Nucleus (VIM) with Tractography in Patients Undergoing MRI-Guided High Intensity Focused Ultrasound (HIFU) Thalamotomy. Ezponda A, Calvo-Imirizaldu M, Malmierca P, Garcia-Eulate R, Zubieta J, Aviles I, Rodriguez Oroz M, Guridi J, Fernandez M, Dominguez Echavarri P.

Radiological Assessment and Monitoring in MRI-Guided High Intensity Focused Ultrasound (HIFU) Thalamotomy: How We Do It. Ezponda A, Calvo-Imirizaldu M, Malmierca P, Garcia-Eulate R, Zubieta J, Fernandez M, Guridi J, Dominguez Echavarri P.

Variable Skull Density Ratio for Transcranial MR-Guided Focused Ultrasound Thalamotomy: Is it Possible to Correlate Different Venders. Hori H, Yamaguchi T, Abe K, Taira T.

A Deeper Impact - Using MR Guided Focused Ultrasound for the Treatment of Essential Tremor Targeting Both Thalamic Ventralis Intermidius Nucleus and the Subthalamic Zona Incerta. Jameel A, Bain P, Nandi D, Jones B, Kirmi O, Gedroyc W.

Treating Tremors with Ultrasound? How, What, Why and Where? An Introduction to Magnetic Resonance-Guided Focused Ultrasound for Movement Disorders. Jameel A, Bain P, Nandi D, Jones B, Kirmi O, Ramji S, Gedroyc W.

Blood-Brain Barrier Opening in the Hippocampus and Entorhinal Cortex Using MR-Guided Focused Ultrasound in Patients with Alzheimer's Disease. Mehta R, Rezai A, Haut M, Najib U, Ranjan M, Marano G, Dayan M, Kelm N, Hou B, Wang P, Carpenter J.

Functional and Structural Integrity Following Focused Ultrasound Thalamotomy and Its Correlation with Tremor Relief. Zur G, Lesman O, Kahn I, Eran A.\


Cancer, Including Prostate Cancer (4)

Combined Treatment of Chemotherapy (Gem/nPac) and Focused Ultrasound for Unresectable Pancreatic Cancer: Prospective Study for Safety and Initial Efficacy. Lee J, Oh D, Lee K, Lee S, Kang S, Son K, Han J.

High-Intensity Focused Ultrasound (HIFU) Focal Therapy to Primary Treatment of Localized Prostate Cancer Using 68Ga-PSMA PET/MR as Main Guidance: Innovative Experience in 14 Patients. Mariotti G, Kayano P, Falsarella P, Claros O, Cunha M, Lemos G, Queiroz M, Garcia R, Baroni R, Carneiro A.

Day-Clinic High-Intensity Focused Ultrasound (HIFU) Focal Therapy to Primary Treatment of Localized Prostate Cancer: Initial Experience of 37 Patients. Mariotti G, Kayano P, Falsarella P, Claros O, Lemos G, Queiroz M, Garcia R, Baroni R, Carneiro A.

Radiosensitization of Human Cancer Cells in Vitro with Focused Ultrasound Induced Hyperthermia. Zhang X, Unger M, Patties I, Landgraf L, Melzer A.


Uterine Fibroids and Women’s Health (12)

MR-Guided Focused Ultrasound (MRgFUS) Compared to the Main Current Therapeutic Approaches for the Treatment of Uterine Fibroids. Alfieri G, Leonardi A, Napoli A, Scipione R, Dababou S, Catalano C.

The Treatment of Submucosal Uterine Fibroids by Using Magnetic Resonance-Guided Focused Ultrasound Surgery (MRgFUS): The Evaluation of Efficacy and Safety in 3-Year Prospective Study. Cobianchi Bellisari F, Iafrate S, Capretti I, Cannizzaro E, de Matteis F, Arrigoni F, Di Luzio M, Mascaretti S, Masciocchi C.

Magnetic Resonance-Guided Focused Ultrasound Surgery (MRgFUS) Ablate Adenomyosis Combined with Gonadotropin-Releasing Hormone Agonist: A Clinical Study. Huang Y.

Treatment of Type 2 and 3 Uterine Fibroids with MR-Guided Focused Ultrasound Surgery: Study of 248 Fibroids. Kakkar R, Desai S.

Assessment of Semiquantitative Parameters of Dynamic Contrast-Enhanced Perfusion MR Imaging in Predicting the Nonperfused Volume Ratio of at Least 80%: High-Intensity Focused Ultrasound Ablation of Uterine Fibroids. Keserci, B, Minh Duc, N.

The Impact of Tissue Characteristics on Outcome of High-Intensity Focused Ultrasound Treatment of Uterine Leiomyomas. Keserci B, Minh Duc N, Firwana Y, Nadarajan C, Chopra R.

High-intensity Focused Ultrasound in the Treatment of Uterine Fibroids. Lam A.

Effects of Oxytocin on High-Intensity Focused Ultrasound Ablation of Leiomyoma: A Clinical Trial Study. Minh Duc N, Chopra R, Keserci B.

The Efficacy and Safety of Magnetic Resonance-Guided High-Intensity Focused Ultrasound Ablation of Pedunculated Subserosal Leiomyoma. Minh Duc N, Chopra R, Keserci B.

Impact of Tissue Vascularity on the Outcome of High-Intensity Focused Ultrasound (HIFU) Treatment of Adenomyosis. Minh Duc N, Chopra R, Nadarajan C, Abdullah M, Keserci B.

The Influence of High-Intensity Focused Ultrasound Ablation of Uterine Diseases with an Immediate Non-Perfused Volume Ratio > 90% on Ovarian Reserve. Minh Duc N, Nadarajan C, Abdullah M, Chopra R, Keserci B.

The Role of Magnetic Resonance Imaging in Predicting the Outcome of High-Intensity Focused Ultrasound Treatment of Adenomyosis. Minh Duc N, Nadarajan C, Huy H, Chopra R, Keserci B.


Bone/Orthopedic (1)

Efficacy of MR-Guided Focused Ultrasound Surgery in Facetal Arthropathy: A Study of 21 Patients. Kakkar R, Karnavat C, Desai S.


Thyroid (1)

Different Ablative Techniques for Benign Thyroid Nodules. Mauri G.

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