
Focused ultrasound might hold the clue. Using it to modulate the properties of the BBB allowed the researchers to deliver 489 ng/mg of IVIg to the target brain area using two treatments a week apart. While all treatment groups showed a significant reduction in amyloid plaque pathology, the group receiving the IVIg-focused ultrasound treatment was the only one that significantly promoted neuronal proliferation and survival. What is the next step for translation of these promising results? Stay tuned!
See the Proceedings of the National Academy of Sciences (PNAS) >
See the Sunnybrook Research Institute Press Release >
See Hang Yu Lin’s Animated BBB Opening Video and Read Her Profile >
See Media Coverage of this Story in Medical Xpress >