Improvement of Glymphatic-lymphatic Drainage of Beta-amyloid by Focused Ultrasound in Alzheimer’s Disease Model

Along with their nuclear medicine colleagues, the focused ultrasound and biomedical research teams at Seoul National University in Korea conducted preclinical studies to confirm the mechanism of action that decreases beta-amyloid plaque accumulation in a mice model of dementia after applying focused ultrasound plus microbubbles to open the blood-brain barrier. Their findings suggest that the glymphatic-lymphatic system drains, or clears, beta-amyloid from the brain to the cerebral spinal fluid to delay the progression of dementia. See the Confirmatory Results section of the bioRxiv Neuroscience preprint server >

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