Magnetic Resonance Guided High Intensity Focused Ultrasound for Head and Neck Cancer - A Pilot Study

Project Name: Magnetic Resonance Guided High Intensity Focused Ultrasound for Head and Neck Cancer - A Pilot Study
Status: Active
Primary Site: Sunnybrook Health Sciences Centre
Sponsor Organization: FUSF Research Awards Committee
Funded Date: Dec 01, 2013
Funding Program: Research Award
Funding Period: Dec 01, 2013 - Jun 01, 2016
Amount Awarded: $71,800.00
Category: Head and neck cancer

Abstract

Head and neck cancer is the sixth most common form of malignancy world-wide. Surgery, chemotherapy and radiation are typically associated with at least seven weeks of treatment and a high burden of side effects. Tumour recurrence within the primary site or the neck continues to be the most common cause of treatment failure. There remains a need for therapeutic strategies which can improve loco-regional control and provide symptom relief while limiting treatment duration and side effects. This clinical pilot study will utilize magnetic resonance guided focused ultrasound to treat cancer of the head and neck, prior to standard palliative radiotherapy andd/or chemotherapy treatments. If proven safe and technically feasible, MRFUS for head and neck cancer has the potential to drastically decrease side effects and treatment time while improving tumour cure rates. Future applications could include focused ultrasound alone, in combination with current treatments or as a mechanism for precise drug delivery.

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