Feasibility of MR guided Lung Cancer ablation using saline flooded lung

Project Name: Feasibility of MR guided Lung Cancer ablation using saline flooded lung
Status: Complete
Primary Site: SRH Wald-Klinikum Gera
Sponsor Organization: Focused Ultrasound Foundation
Funded Date: Jun 01, 2014
Funding Period: Jun 01, 2014 - Aug 31, 2015
Funding Program: Research Award
Category: Pre-Clinical
Amount Awarded: $109,100.00


Lung cancer is the most mortal tumor entity, which is preferably treated by surgical resection. Alternative ablation methods (rf, litt) haven't been clinically established by there invasivity. HIFU is not considered as an treatment option in lung due to the air content. Lung flooding generates gas free saline parenchyma compound without damaging the lung. Recently our work showed the usability of ultrasound guided lung cancer hifu ablation. In contrast to ultrasound, MRg-FUS would improve the radically of treatment. Toward the first human pilot, the lung flooding process needs to be optimized for operating in mr environment. Further the usability of mr imaging and thermometry in flooded lung haven't been investigated so far. This research project is aimed to provide fundamental information describing the usability and limitations of MRg-FUS treatment of lung cancer using lung flooding.

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