MR-Guided High Intensity Focused Ultrasound -- Temperature Measurement

Project Name: MR-Guided High Intensity Focused Ultrasound -- Temperature Measurement
Status: Complete
Primary Site: University of Utah
Sponsor Organization: Focused Ultrasound Foundation
Funded Date: Feb 01, 2008
Funding Period: Feb 01, 2008 - Jan 31, 2009
Funding Program: Research Award
Category: Technical
Amount Awarded: $79,936.00


Accurate, near-real-time temperature measurements are essential for effective monitoring of all types of thermal therapies. Current methods are too slow, subject to substantial errors from motion and fail in fat. We propose: 1) To develop a modification of the PRF technique to allow simultaneous measurement of proton longitudinal relaxation rate, T1. 2) To continue the implementation of model-based linear predictive techniques to utilize the best estimate of tissue thermal properties and linear predictive filtering (e.g., Kalman filter) to obtain the current estimate of the temperature distribution from the prior temperature distribution. Tissue thermal properties will be estimated based upon segmentation from multiple MRI contrasts.

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