Heterogeneity correction for improved breast cancer ablation

Project Name: Heterogeneity correction for improved breast cancer ablation
Status: Complete
Primary Site: University Medical Center Utrecht
Sponsor Organization: Focused Ultrasound Foundation
Funded Date: Feb 01, 2011
Funding Period: Feb 01, 2011 - Mar 31, 2012
Funding Program: Research Award
Category: Technical
Amount Awarded: $100,000.00


The treatment of breast cancer by MR guided HIFU has recently shown great potential for clinical practice. Although innovative lateral firing transducer designs allow to significantly reduce the risk of undesired tissue damage to the thoracic cage, the heart and the lung, such a design is typically limited by the aberration effect of the inhomogeneous tissue composition of the breast. This project proposes a correction strategy for this type of aberrations, based on high resolution MRI in conjunction with tissue ultrasound celerity measurements. The method is compatible with clinical practice and has the potential to lead to improved treatment efficiency and increased patient safety for MR guided HIFU ablations of breast cancer.

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