Acoustic activation of the GBM-brain microenvironment for improved T-cell immunotherapy

Project Name: Acoustic activation of the GBM-brain microenvironment for improved T-cell immunotherapy
Status: Active
Primary Site: University of Maryland School of Medicine
Sponsor Organization: Focused Ultrasound Foundation
Funded Date: Apr 01, 2020
Funding Period: Apr 01, 2020 - Apr 01, 2022
Funding Program: Immunotherapy
Category: Pre-Clinical
Amount Awarded: $199,396.00

Abstract

The overall hypothesis of this project is that MRgFUS applied in mechanical modes will shift the GBM microenvironment toward an anti-tumor immunologic state through increases in specific cytokines, immune cell populations, and neoantigen presentation.

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