Foundation Funded Research Projects

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Showing 100 out of 122 research projects
Category Project Name (Click on the project name for more info) Primary Research Site Principal Investigator Funding Dates Program
Psychiatric disorders Phase I trial of MR-guided Focused Ultrasound (MRgFUS) bilateral capsulotomy...
    Jun 05, 2018 - Jun 04, 2020 Brain Program
    Brain tumors, General Safety study: sonodynamic therapy with 5-ALA in a porcine model
      Jun 05, 2018 - Jun 05, 2019 Brain Program
      Brain tumors, General Microvascular Ablation of Intracranial Gliomas with Focused Ultrasound (9L Line)
        Apr 24, 2018 - Apr 24, 2019 Brain Program
        Brain tumors, General Microvascular Ablation of Intracranial Gliomas with Focused Ultrasound (F98...
            Apr 06, 2018 - Apr 06, 2019 Brain Program
            Stroke, Thromboembolic Selective opening of the blood brain barrier using focused ultrasound combined...
              Apr 04, 2018 - Apr 04, 2019 Brain Program
              Brain, General Sonodynamic therapy for treatment of C6 glioma in a rat model proof-of-concept...
                Apr 04, 2018 - Oct 04, 2018 Brain Program
                Brain, General Focused ultrasound for treatment of deep-seated cerebral cavernous malformations
                  Mar 26, 2018 - Mar 26, 2019 Brain Program
                  Soft tissue tumors Investigation of the immunostimulatory response to high intensity focused...
                    Mar 12, 2018 - Mar 12, 2019 Research Award
                    Back & neck pain Focused ultrasound mediated neuromodulation for the treatment of spinal cord...
                      Mar 05, 2018 - Mar 05, 2019 Brain Program
                      Investigation of focused ultrasound mediated enhancement of chronic non-...
                        Feb 12, 2018 - Feb 12, 2019 Research Award
                        General, Technology Laser-generated Focused Ultrasound Transducer for Transcranial Applications
                          Feb 08, 2018 - Apr 22, 2019 Brain Program
                          General, Technology Use of shock-wave exposures for accelerating thermal ablation of targeted...
                            Feb 07, 2018 - Apr 06, 2019 Research Award
                            Bladder tumors Focused Ultrasound Mediated Drug Delivery across the Urothelium
                              Feb 06, 2018 - Feb 05, 2019 Research Award
                              Pancreatic tumors Focused Ultrasound Driven Drug Release From Theranostic Nanoparticles For The...
                                Jan 24, 2018 - Jan 24, 2019 Research Award
                                Accessibility and Benefit of FUS treatment for inoperable Lung Cancer Patients,...
                                  Dec 14, 2017 - Feb 13, 2019 Research Award
                                  Alzheimer’s Disease Effects of FUS on CNS Uptake and Efficacy of an Anti-Amyloid Antibody in Aged...
                                    Nov 30, 2017 - Mar 30, 2018 Research Award
                                    Acoustic Backscatter-based 3D Mapping of Cavitation and Skull Surface in...
                                      Oct 31, 2017 - Dec 31, 2018 Research Award
                                      Back & neck pain Safety and initial feasibility of using the Neurolyser XR device for the...
                                        Sep 26, 2017 - Mar 25, 2019 Research Award
                                        Parkinson’s Disease MRgFUS Blood-Brain Barrier Drug Delivery with AAV2 Gene Therapy Microbubble...
                                          Sep 01, 2017 - Aug 31, 2018 Research Award
                                          Safety and Effectiveness of Sacroiliac Joint Palliation in Swine using MRgFUS
                                            Jul 01, 2017 - Jun 30, 2018 Research Award
                                            Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                              May 17, 2017 - Nov 17, 2017 Brain Program
                                              Brain tumors, Metastasis Focused Ultrasound to Enhance Immunotherapy for Metastatic Brain Melanoma
                                                May 05, 2017 - Sep 04, 2018 Brain Program
                                                Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                  May 01, 2017 - Nov 01, 2017 Brain Program
                                                  Patterning of bone regeneration via ultrasound activation of heat shock-...
                                                    Mar 01, 2017 - Feb 28, 2018 Research Award
                                                    Brain tumors, General A Feasibility Safety Study Using the ExAblate 4000 system in Management of...
                                                      Feb 27, 2017 - Feb 26, 2019 Brain Program
                                                      Acoustic Parameters of Bone as a function of HU and MRI
                                                        Feb 20, 2017 - Feb 21, 2018 Brain Program
                                                        Alzheimer’s Disease
                                                          Jan 12, 2017 - Jan 11, 2019 Brain Program
                                                          Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                            Nov 29, 2016 - May 19, 2017 Brain Program
                                                            Real-time Treatment Monitoring by Diffusion MRI
                                                              Nov 29, 2016 - Nov 28, 2017 Brain Program
                                                              Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                Nov 07, 2016 Brain Program
                                                                Brain, General FUS-mediated Neuromodulation from Unanesthetized Freely-moving Animals
                                                                  Oct 01, 2016 - Sep 30, 2017 Research Award
                                                                  Pancreatic tumors Defining Basic Properties of Physical Immunotherapy using HIFU and Immune...
                                                                    Sep 07, 2016 - Jun 07, 2019 Immunotherapy
                                                                    Parkinson’s Disease Antibody Delivery Through the BBB Opening in an Alpha-Synuclein Model
                                                                      Aug 15, 2016 - Oct 15, 2017 Brain Program
                                                                      Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                        Aug 15, 2016 - Feb 15, 2017 Brain Program
                                                                        Massively Parallel Nonlinear Ultrasound Simulation of Histotripsy in the Brain
                                                                          Jul 18, 2016 - Jul 18, 2017 Brain Program
                                                                          Liver tumors A novel genetic reprogramming therapy for hepatocellular carcinoma using...
                                                                            Jul 01, 2016 - Jun 30, 2017 Research Award
                                                                            Brain tumors, Glioblastoma Ultrasound-mediated delivery of siRNA for enhancing temozolomide efficacy...
                                                                              Jun 01, 2016 - Dec 15, 2017 Research Award
                                                                              Parkinson’s Disease Minimally-Invasive Therapy for Parkinson’s Disease Achieved by the Focused U...
                                                                                Feb 04, 2016 - Feb 03, 2017 Brain Program
                                                                                General, Cancer Ultrasound ablation combined with immunotherapy: priming to enhance efficacy
                                                                                  Feb 01, 2016 - Jan 31, 2017 Brain Program
                                                                                  Alzheimer’s Disease Effects of FUS on CNS Uptake and Efficacy of an Anti-Amyloid Antibody in Aged...
                                                                                    Feb 01, 2016 - Jan 31, 2017 Brain Program
                                                                                    Brain, General Development and Calibration of MR Techniques for In-Vivo Bone Thermometry
                                                                                      Feb 01, 2016 - Jan 31, 2017 Brain Program
                                                                                      Neuro Focused Ultrasound MR Coil Fabrication and Testing
                                                                                        Jan 06, 2016 - Apr 06, 2017 Brain Program
                                                                                        Kidney tumors Evaluation of the Systemic Response to Boiling Histotripsy Treatment for Renal...
                                                                                          Dec 01, 2015 - Apr 30, 2017 Research Award
                                                                                          Brain tumors, General A Chronic Pig Study of Transcranial Histotripsy for Treatment of Brain Tumors
                                                                                            Nov 11, 2015 - Dec 18, 2015 Brain Program
                                                                                            General, Cancer The Focused ultrasound mediated immune responses in metastatic melanoma
                                                                                              Nov 01, 2015 - Nov 01, 2017 Brain Program
                                                                                              Brain, General Neuronavigation-guided and Ultrasound-Monitored Human BBB-opening Focused...
                                                                                                Nov 01, 2015 - Oct 31, 2016 Brain Program
                                                                                                Brain, General Transcranial Histotripsy for Treatment of Brain Tumors
                                                                                                  Oct 21, 2015 - Feb 21, 2016 Brain Program
                                                                                                  Brain, General Method for fully 3D volumetric thermometry, with application to transcranial...
                                                                                                    Oct 09, 2015 - Oct 08, 2016 Brain Program
                                                                                                    Bone, Non-metastases Pediatric Focused Ultrasound Computational Data Center and Registry
                                                                                                      Oct 01, 2015 - Dec 31, 2017 Research Award
                                                                                                      Back & neck pain Low Intensity Pulsed Ultrasound (LIPUS) for the Treatment of Spinal Disc...
                                                                                                        Oct 01, 2015 - Sep 30, 2016 Research Award
                                                                                                        Brain, General Thermal Dose Experiment in a Pig Model
                                                                                                          Jul 24, 2015 - Feb 19, 2016 Brain Program
                                                                                                          Movement Disorders, General Modulated focused ultrasound for treatment of de-myelinating axons in multiple...
                                                                                                            Jun 01, 2015 - Nov 30, 2016 Research Award
                                                                                                            Atrial Fibrillation Trans-Esophageal Cardiac Ablation Using High Intensity Focused Ultrasound: A...
                                                                                                              Jun 01, 2015 - Nov 30, 2016 Research Award
                                                                                                              Back & neck pain Treatment of facetogenic lumbar back pain
                                                                                                                Mar 02, 2015 - Mar 01, 2016 Research Award
                                                                                                                General, Cancer Sonodynamic therapy for treatment of C6 glioma in a rat model – Step 2: P...
                                                                                                                  Feb 12, 2015 - Feb 11, 2016 Brain Program
                                                                                                                  Parkinson’s Disease Focused Ultrasound for Increased Delivery of Intranasal DNA Nanoparticles to...
                                                                                                                    Feb 01, 2015 - Jan 31, 2017 Research Award
                                                                                                                    Brain, General Enhancement of FUS Mediated Delivery of Stem Cells to Brain
                                                                                                                      Feb 01, 2015 - Jan 31, 2016 Research Award
                                                                                                                      Brain, General Noninvasive targeted neuromodulation and functional imaging in behaving macaques
                                                                                                                        Feb 01, 2015 - Jul 30, 2016 Research Award
                                                                                                                        Brain tumors, General MR-Guided Ultrasound Neurosurgery for the Treatment of Brain Tumors
                                                                                                                          Nov 10, 2014 - Nov 09, 2016 Brain Program
                                                                                                                          Bone, Non-metastases Magnetic Resonance-Guided High Intensity Focused Ultrasound for Pain Management...
                                                                                                                            Sep 12, 2014 - Sep 11, 2015 Research Award
                                                                                                                            Microbubble cloud formation from ultrasound contrast agents during histotripsy...
                                                                                                                              Aug 01, 2014 - Nov 30, 2015 Research Award
                                                                                                                              General, Technology Image-guided Non-invasive Ultrasonic Thrombolysis Using Histotripsy
                                                                                                                                Jul 01, 2014 - Jun 30, 2018 Research Award
                                                                                                                                Brain, General Non-Invasive Treatment of Pediatric Neurological Disorders using MR-guided...
                                                                                                                                  Jul 01, 2014 - Jun 30, 2015 Research Award
                                                                                                                                  General, Cancer Sonodynamic therapy for treatment of C6 glioma in a rat model – Step 1: F...
                                                                                                                                    Jun 03, 2014 - Sep 03, 2014 Brain Program
                                                                                                                                    Uterine fibroids Accelerated focused ultrasound ablation of uterine fibroids with MR guided...
                                                                                                                                        Jun 01, 2014 - May 31, 2016 Research Award
                                                                                                                                        Brain, General MR Temperature Imaging Toolbox for Focused Ultrasound Neurosurgery
                                                                                                                                          Jun 01, 2014 - May 31, 2016 Research Award
                                                                                                                                          General, Cancer Feasibility of MR guided Lung Cancer ablation using saline flooded lung
                                                                                                                                            Jun 01, 2014 - Aug 31, 2015 Research Award
                                                                                                                                            General, Cancer Deep Penetrating Triggered Release Nanoparticles As Tumor Radiosensitizers
                                                                                                                                              Dec 01, 2013 - Nov 30, 2014 Research Award
                                                                                                                                              Head and neck cancer Magnetic Resonance Guided High Intensity Focused Ultrasound for Head and Neck...
                                                                                                                                                Dec 01, 2013 - Jun 01, 2016 Research Award
                                                                                                                                                Brain tumors, Metastasis A Feasibility Study to Evaluate the Safety and Feasibility of Transcranial...
                                                                                                                                                    Jul 12, 2013 - Nov 01, 2015 Brain Program
                                                                                                                                                    General, Technology Nanoagents for improving focused ultrasound thermal delivery to tumors with...
                                                                                                                                                      Jul 01, 2013 - Dec 15, 2014 Research Award
                                                                                                                                                      Prostate The Effect of Focused Ultrasound Ablation on Adjacent Nerve Function
                                                                                                                                                        Jun 30, 2013 - May 31, 2018 Research Award
                                                                                                                                                        Osteoarthritis Pain Alleviation of Magnetic Resonance-guided Focused Ultrasound Surgery...
                                                                                                                                                          Jun 10, 2013 - Jun 01, 2016 Research Award
                                                                                                                                                          General, Technology Real-time 3D MR Thermometry for Focused Ultrasound Surgery
                                                                                                                                                            Jun 10, 2013 - Jun 09, 2014 Research Award
                                                                                                                                                            FUS-mediated Functional Neuromodulation for Neurophysiologic Assessment in a...
                                                                                                                                                              Jun 01, 2013 - May 31, 2014 Research Award
                                                                                                                                                              Epilepsy Target-Specific FUS Treatment Envelope Survey in Cadaveric and Ex-Vivo...
                                                                                                                                                                Mar 26, 2013 - Jun 25, 2013 Brain Program
                                                                                                                                                                Prostate MR Directed Focal Hyperthermia for Pelvic Disease
                                                                                                                                                                  Dec 01, 2012 - Dec 10, 2014 Research Award
                                                                                                                                                                  A New Application for MR-guided Focused Ultrasound: Amplification and...
                                                                                                                                                                    Nov 01, 2012 - Oct 31, 2014 Research Award
                                                                                                                                                                    Brain, General In vivo transcranial cavitation study of low-frequency focused ultrasound in...
                                                                                                                                                                      Sep 17, 2012 - Sep 16, 2013 Brain Program
                                                                                                                                                                      Parkinson’s Disease A Feasibility Study to Evaluate Safety and Initial Effectiveness of ExAblate...
                                                                                                                                                                          Sep 12, 2012 - Dec 12, 2013 Brain Program
                                                                                                                                                                          Brain, General Phase Aberration Correction for Transcranial MRgFUS using a Hybrid Simulation...
                                                                                                                                                                            Aug 17, 2012 - Aug 16, 2013 Brain Program
                                                                                                                                                                            Alzheimer's Disease Blood-brain barrier opening for facilitating drug delivery in neurological and...
                                                                                                                                                                              Aug 01, 2012 - Jul 31, 2013 Research Award
                                                                                                                                                                              Pancreatic tumors MR-guided HIFU enhanced targeted drug delivery for treatment of pancreas...
                                                                                                                                                                                Mar 09, 2012 Liver/Pancreas Program
                                                                                                                                                                                Brain tumors, General Targeted Delivery of Controlled Release Nanoparticles to Brain Tumors Using...
                                                                                                                                                                                  Jan 01, 2012 - Dec 31, 2017 Research Award
                                                                                                                                                                                  Uterine fibroids Updated Costs of Uterine Fibroid Treatments Including Focused Ultrasound Surgery
                                                                                                                                                                                    Nov 15, 2011 - Nov 14, 2012 Research Award
                                                                                                                                                                                    Brain tumors, General Tests of microbubble-enhanced ablation in a large animal model with a...
                                                                                                                                                                                      Oct 01, 2011 - Dec 31, 2012 Research Award
                                                                                                                                                                                      Brain, General Detection and Characterization of Intracranial Cavitation Activity
                                                                                                                                                                                        Aug 01, 2011 - Jul 31, 2012 Brain Program
                                                                                                                                                                                        General, Cancer Hypoxia-directed Magnetic Resonance-guided Focused Ultrasound Therapy
                                                                                                                                                                                          Aug 01, 2011 - Jan 31, 2013 Research Award
                                                                                                                                                                                          Brain, General Study of standing waves and secondary focal spots
                                                                                                                                                                                            Jun 15, 2011 Brain Program
                                                                                                                                                                                            Brain tumors, Metastasis A Study to Evaluate the Safety and Feasibility of Transcranial MRI-Guided...
                                                                                                                                                                                              Jun 15, 2011 - Jun 15, 2012 Brain Program
                                                                                                                                                                                              Essential Tremor A Feasibility Study to Evaluate Safety and Initial Effectiveness of ExAblate...
                                                                                                                                                                                                Jun 13, 2011 - Jun 13, 2012 Brain Program
                                                                                                                                                                                                Pancreatic tumors Image-Guided Drug Delivery to Tumors using Ultrasound-Activated Perfluorocarbon...
                                                                                                                                                                                                  Apr 15, 2011 - Jul 15, 2012 Research Award
                                                                                                                                                                                                  Brain tumors, General Delivery of Brain Tumor-Penetrating Nanoparticles Across the Blood Brain...
                                                                                                                                                                                                    Apr 01, 2011 - Dec 31, 2012 Research Award
                                                                                                                                                                                                    Essential Tremor A safety and feasibility study of MR-guided focused ultrasound lesioning in the...
                                                                                                                                                                                                      Apr 01, 2011 - Jun 30, 2012 Research Award
                                                                                                                                                                                                      Brain, General Direct Correction of Transcranial Ultrasonic Focusing Based on MR-ARFI Guidance
                                                                                                                                                                                                        Mar 21, 2011 Brain Program
                                                                                                                                                                                                        Metabolic Disorders, General MR-Guided Focused Ultrasound Ablation of Visceral Fat: A new treatment for...
                                                                                                                                                                                                          Mar 15, 2011 - Mar 14, 2012 Research Award
                                                                                                                                                                                                          Essential Tremor A Feasibility Study to Evaluate Safety and Initial Effectiveness of ExAblate...
                                                                                                                                                                                                            Feb 07, 2011 Brain Program
                                                                                                                                                                                                            Breast tumors Heterogeneity correction for improved breast cancer ablation
                                                                                                                                                                                                              Feb 01, 2011 - Mar 31, 2012 Research Award
                                                                                                                                                                                                              Brain, General Method for fully 3D volumetric thermometry, with application to transcranial...
                                                                                                                                                                                                                Jan 27, 2011 Brain Program
                                                                                                                                                                                                                Essential Tremor A Radiographic and Histologic Comparison Between Radiofrequency, Gamma Knife...
                                                                                                                                                                                                                  Dec 01, 2010 - Feb 28, 2012 Research Award
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