Foundation Funded Research Projects

Enter your search criteria below and then click the Search button.

Showing 100 out of 163 research projects
Category Project Name (Click on the project name for more info) Primary Research Site Principal Investigator Funding Dates Program
Adjuvant Focused Ultrasound to Promote Immunotherapy Response for...
    Nov 22, 2019 - May 21, 2022 Immunotherapy
    Histotripsy tumor ablation-mediated immune-stimulation
      Nov 06, 2019 - Nov 06, 2020 Immunotherapy
      A Study to Evaluate the Safety and Feasibility of Blood-Brain Barrier...
        Oct 31, 2019 - Oct 30, 2021 Brain Program
        Alzheimer’s Disease A Phase I/IIa Study: Feasibility of Blood-Brain Barrier Opening in the...
          Oct 30, 2019 - Oct 29, 2021 Brain Program
          MRI Guidance of Focused Ultrasound Neurosurgery
            Oct 24, 2019 - Jan 24, 2022 Brain Program
            MRI of Skull Heating During Focused Ultrasound Neurosurgery
              Oct 24, 2019 - Jan 24, 2022 Brain Program
              Development of Novel Acoustic Coupling Media to Improve Image Guidance and...
                Oct 24, 2019 - Jan 24, 2021 Research Award
                Focused ultrasound stimulation of the immune response in a breast cancer model
                  Oct 16, 2019 - Oct 16, 2020 Immunotherapy
                  Focused ultrasound stimulation of the immune response in cancer models
                    Oct 16, 2019 - Oct 16, 2020 Immunotherapy
                    Transcranial Histotripsy for Treatment of Brain Tumors – Initial In-vivo Pig S...
                      Oct 01, 2019 - Sep 30, 2020 Brain Program
                      Investigating the Feasibility of Targeting Temporal Lobe using Transcranial...
                        Sep 13, 2019 - Sep 12, 2020 Brain Program
                        Blood Brain Barrier (BBB) Opening of Rat by Laser-generated Focused Ultrasound...
                          Sep 10, 2019 - Mar 10, 2021 Brain Program
                          aCD40 + ablation trial
                            Sep 01, 2019 - Sep 01, 2020 Immunotherapy
                            Treating veterinary cancer patients with focused ultrasound
                              Jun 01, 2019 - Jun 01, 2020 Veterinary
                              Non-Invasive Surgical Treatment of Lung Cancer
                                May 21, 2019 - Jul 20, 2020 Research Award
                                FUS for therapy of Neuromyelitis Optica – an inflammatory demyelinating d...
                                  Mar 25, 2019 - Mar 24, 2020 Research Award
                                  Brain tumors, Glioblastoma Focused ultrasound immunomodulation for pancreatic cancer
                                    Mar 12, 2019 - Mar 12, 2020 Immunotherapy
                                    Brain, General Microbubble enhanced FUS treatments in the brain: impact of bubble distribution...
                                      Mar 01, 2019 - Mar 01, 2020 Brain Program
                                      Convective skin-cooling device for use with existing MRgFUS systems to prevent...
                                        Feb 28, 2019 - Nov 01, 2019 Research Award
                                        Microbubble distribution in the brain: a real-time intra-operative map to...
                                          Feb 21, 2019 - Feb 21, 2020 Brain Program
                                          Parkinson’s Disease MRGFUS GENE DELIVERY FOR NEUROPROTECTION IN PARKINSON'S DISEASE
                                              Jan 18, 2019 - Jan 18, 2020 Brain Program
                                              Development of a turnkey USgFUS preclinical research platform
                                                Jan 04, 2019 - Jan 03, 2020 Research Award
                                                Drug delivery strategies using drug-loaded extracellular vesicles generated by...
                                                  Dec 11, 2018 - Dec 10, 2019 Research Award
                                                  Movement Disorders, General Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy for Tremor...
                                                    Sep 28, 2018 - Sep 27, 2019 Research Award
                                                    Psychiatric disorders A Phase 1 Trial of MR-guided Focused Ultrasound (MRgFUS) Bilateral Capsulotomy...
                                                      Sep 27, 2018 - Sep 26, 2020 Brain Program
                                                      Liver tumors Non-invasive Focused Ultrasound Ablation for the Treatment of...
                                                        Sep 13, 2018 - Aug 30, 2020 Research Award
                                                        Non-invasive varicose vein treatment by HIFU under ultrasound guidance: Phase...
                                                          Sep 13, 2018 - Sep 12, 2019 Research Award
                                                          Psychiatric disorders Phase I trial of MR-guided Focused Ultrasound (MRgFUS) bilateral capsulotomy...
                                                            Jun 05, 2018 - Jun 04, 2020 Brain Program
                                                            Brain tumors, General Safety study: sonodynamic therapy with 5-ALA in a porcine model
                                                              Jun 05, 2018 - Jun 05, 2019 Brain Program
                                                              Brain tumors, Glioblastoma Safety evaluation of irinotecan delivery to a rat glioma model using a clinical...
                                                                Jun 04, 2018 - Aug 04, 2019 Research Award
                                                                Epilepsy Focused ultrasound thalamotomy for the prevention of secondary generalization...
                                                                  Jun 01, 2018 - May 31, 2018 Brain Program
                                                                  Brain tumors, General Microvascular Ablation of Intracranial Gliomas with Focused Ultrasound (9L Line)
                                                                    Apr 24, 2018 - Apr 24, 2019 Brain Program
                                                                    Brain tumors, General Microvascular Ablation of Intracranial Gliomas with Focused Ultrasound (F98...
                                                                        Apr 06, 2018 - Apr 06, 2019 Brain Program
                                                                        Stroke, Thromboembolic Selective opening of the blood brain barrier using focused ultrasound combined...
                                                                          Apr 04, 2018 - Apr 04, 2019 Brain Program
                                                                          Brain, General Sonodynamic therapy for treatment of C6 glioma in a rat model proof-of-concept...
                                                                            Apr 04, 2018 - Oct 04, 2018 Brain Program
                                                                            Brain, General Focused ultrasound for treatment of deep-seated cerebral cavernous malformations
                                                                              Mar 26, 2018 - Mar 26, 2019 Brain Program
                                                                              Epilepsy Use of low-intensity focused ultrasound for the non-invasive, focal...
                                                                                Mar 18, 2018 - Jun 18, 2018 Research Award
                                                                                Soft tissue tumors Investigation of the immunostimulatory response to high intensity focused...
                                                                                  Mar 12, 2018 - Mar 01, 2020 Veterinary
                                                                                  Back & neck pain Focused ultrasound mediated neuromodulation for the treatment of spinal cord...
                                                                                    Mar 05, 2018 - Mar 05, 2019 Brain Program
                                                                                    Investigation of focused ultrasound mediated enhancement of chronic non-...
                                                                                      Feb 12, 2018 - Feb 12, 2019 Veterinary
                                                                                      General, Technology Laser-generated Focused Ultrasound Transducer for Transcranial Applications
                                                                                        Feb 08, 2018 - Apr 22, 2019 Brain Program
                                                                                        General, Technology Use of shock-wave exposures for accelerating thermal ablation of targeted...
                                                                                          Feb 07, 2018 - Apr 06, 2019 Research Award
                                                                                          Bladder tumors Focused Ultrasound Mediated Drug Delivery across the Urothelium
                                                                                            Feb 06, 2018 - Feb 05, 2019 Research Award
                                                                                            Pancreatic tumors Focused Ultrasound Driven Drug Release From Theranostic Nanoparticles For The...
                                                                                              Jan 24, 2018 - Jan 24, 2019 Research Award
                                                                                              Accessibility and Benefit of FUS treatment for inoperable Lung Cancer Patients,...
                                                                                                Dec 14, 2017 - Feb 13, 2019 Research Award
                                                                                                Alzheimer’s Disease Effects of FUS on CNS Uptake and Efficacy of an Anti-Amyloid Antibody in Aged...
                                                                                                  Nov 30, 2017 - Mar 30, 2018 Research Award
                                                                                                  Acoustic Backscatter-based 3D Mapping of Cavitation and Skull Surface in...
                                                                                                    Oct 31, 2017 - Dec 31, 2018 Research Award
                                                                                                    Back & neck pain Safety and initial feasibility of using the Neurolyser XR device for the...
                                                                                                      Sep 26, 2017 - Mar 25, 2019 Research Award
                                                                                                      Parkinson’s Disease MRgFUS Blood-Brain Barrier Drug Delivery with AAV2 Gene Therapy Microbubble...
                                                                                                        Sep 01, 2017 - Aug 31, 2018 Research Award
                                                                                                        Safety and Effectiveness of Sacroiliac Joint Palliation in Swine using MRgFUS
                                                                                                          Jul 01, 2017 - Jun 30, 2018 Research Award
                                                                                                          Bone, Non-metastases Comparative Study - FUS vs. RF ablation
                                                                                                            Jun 01, 2017 - May 31, 2020 Liver/Pancreas Program
                                                                                                            Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                                              May 17, 2017 - Nov 17, 2017 Immunotherapy
                                                                                                              Brain tumors, Metastasis Focused Ultrasound to Enhance Immunotherapy for Metastatic Brain Melanoma
                                                                                                                May 05, 2017 - Sep 04, 2018 Immunotherapy
                                                                                                                Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                                                  May 01, 2017 - Nov 01, 2017 Immunotherapy
                                                                                                                  Parkinson’s Disease A Prospective, Randomized, Sham Controlled Study to Evaluate the Safety and...
                                                                                                                    Mar 01, 2017 - Sep 01, 2020 Brain Program
                                                                                                                    Patterning of bone regeneration via ultrasound activation of heat shock-...
                                                                                                                      Mar 01, 2017 - Feb 28, 2018 Research Award
                                                                                                                      Brain tumors, General A Feasibility Safety Study Using the ExAblate 4000 system in Management of...
                                                                                                                        Feb 27, 2017 - Feb 26, 2019 Brain Program
                                                                                                                        Acoustic Parameters of Bone as a function of HU and MRI
                                                                                                                          Feb 20, 2017 - Feb 21, 2018 Brain Program
                                                                                                                          Neuropathic pain Phase 1 Clinical Trial of MR Guided Focused Ultrasound (FUS) Thalamotomy of...
                                                                                                                            Jan 19, 2017 - Jul 19, 2019 Brain Program
                                                                                                                            Alzheimer’s Disease A Study to Evaluate the Safety and Feasibility of Blood-Brain Barrier (BBB)...
                                                                                                                              Jan 12, 2017 - Jan 11, 2019 Brain Program
                                                                                                                              Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                                                                Nov 29, 2016 - May 19, 2017 Brain Program
                                                                                                                                Real-time Treatment Monitoring by Diffusion MRI
                                                                                                                                  Nov 29, 2016 - Nov 28, 2017 Brain Program
                                                                                                                                  Ultrasound-induced immune response on breast cancer
                                                                                                                                    Nov 28, 2016 - Nov 28, 2020 Immunotherapy
                                                                                                                                    Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                                                                      Nov 07, 2016 - Nov 07, 2017 Brain Program
                                                                                                                                      Brain, General FUS-mediated Neuromodulation from Unanesthetized Freely-moving Animals
                                                                                                                                        Oct 01, 2016 - Sep 30, 2017 Research Award
                                                                                                                                        Pancreatic tumors Defining Basic Properties of Physical Immunotherapy using HIFU and Immune...
                                                                                                                                          Sep 07, 2016 - Jun 07, 2019 Immunotherapy
                                                                                                                                          Parkinson’s Disease Antibody Delivery Through the BBB Opening in an Alpha-Synuclein Model
                                                                                                                                            Aug 15, 2016 - Oct 15, 2017 Brain Program
                                                                                                                                            Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                                                                              Aug 15, 2016 - Feb 15, 2017 Immunotherapy
                                                                                                                                              Massively Parallel Nonlinear Ultrasound Simulation of Histotripsy in the Brain
                                                                                                                                                Jul 18, 2016 - Jul 18, 2017 Brain Program
                                                                                                                                                Liver tumors A novel genetic reprogramming therapy for hepatocellular carcinoma using...
                                                                                                                                                  Jul 01, 2016 - Jan 30, 2020 Veterinary
                                                                                                                                                  Epilepsy A Feasibility Study to Evaluate Safety and Initial Effectiveness or MR-Guided...
                                                                                                                                                    Jun 16, 2016 - Jun 16, 2018 Brain Program
                                                                                                                                                    Brain tumors, Glioblastoma Ultrasound-mediated delivery of siRNA for enhancing temozolomide efficacy...
                                                                                                                                                      Jun 01, 2016 - Dec 15, 2017 Research Award
                                                                                                                                                      Parkinson’s Disease Minimally-Invasive Therapy for Parkinson’s Disease Achieved by the Focused U...
                                                                                                                                                        Feb 04, 2016 - Feb 03, 2017 Brain Program
                                                                                                                                                        General, Cancer Ultrasound ablation combined with immunotherapy: priming to enhance efficacy
                                                                                                                                                          Feb 01, 2016 - Jan 31, 2017 Brain Program
                                                                                                                                                          Brain, General Development and Calibration of MR Techniques for In-Vivo Bone Thermometry
                                                                                                                                                            Feb 01, 2016 - Aug 16, 2018 Brain Program
                                                                                                                                                            Alzheimer’s Disease Effects of FUS on CNS Uptake and Efficacy of an Anti-Amyloid Antibody in Aged...
                                                                                                                                                              Feb 01, 2016 - Jan 31, 2017 Brain Program
                                                                                                                                                              Brain, General Neuro Focused Ultrasound MR Coil Fabrication and Testing
                                                                                                                                                                Jan 06, 2016 - Apr 06, 2018 Brain Program
                                                                                                                                                                Kidney tumors Evaluation of the Systemic Response to Boiling Histotripsy Treatment for Renal...
                                                                                                                                                                  Dec 01, 2015 - Apr 30, 2017 Research Award
                                                                                                                                                                  Brain tumors, General A Chronic Pig Study of Transcranial Histotripsy for Treatment of Brain Tumors
                                                                                                                                                                    Nov 11, 2015 - Dec 18, 2015 Brain Program
                                                                                                                                                                    General, Cancer The Focused ultrasound mediated immune responses in metastatic melanoma
                                                                                                                                                                      Nov 01, 2015 - Nov 01, 2017 Brain Program
                                                                                                                                                                      Brain, General Neuronavigation-guided and Ultrasound-Monitored Human BBB-opening Focused...
                                                                                                                                                                        Nov 01, 2015 - Oct 31, 2016 Brain Program
                                                                                                                                                                        Brain, General Transcranial Histotripsy for Treatment of Brain Tumors
                                                                                                                                                                          Oct 21, 2015 - Feb 21, 2016 Brain Program
                                                                                                                                                                          Brain, General Method for fully 3D volumetric thermometry, with application to transcranial...
                                                                                                                                                                            Oct 09, 2015 - Oct 08, 2016 Brain Program
                                                                                                                                                                            Back & neck pain Low Intensity Pulsed Ultrasound (LIPUS) for the Treatment of Spinal Disc...
                                                                                                                                                                              Oct 01, 2015 - Sep 30, 2016 Research Award
                                                                                                                                                                              Bone, Non-metastases Pediatric Focused Ultrasound Computational Data Center and Registry
                                                                                                                                                                                Oct 01, 2015 - Dec 31, 2017 Research Award
                                                                                                                                                                                Brain, General Thermal Dose Experiment in a Pig Model
                                                                                                                                                                                  Jul 24, 2015 - Feb 19, 2016 Brain Program
                                                                                                                                                                                  Brain tumors, Metastasis Enhancing immune therapy for brain metastases with focused ultrasound
                                                                                                                                                                                    Jun 01, 2015 - May 31, 2018
                                                                                                                                                                                    Movement Disorders, General Modulated focused ultrasound for treatment of de-myelinating axons in multiple...
                                                                                                                                                                                      Jun 01, 2015 - Nov 30, 2016 Research Award
                                                                                                                                                                                      Atrial Fibrillation Trans-Esophageal Cardiac Ablation Using High Intensity Focused Ultrasound: A...
                                                                                                                                                                                        Jun 01, 2015 - Nov 30, 2016 Research Award
                                                                                                                                                                                        Parkinson’s Disease A feasibility Study to Evaluate Safety and Initial Effectiveness of ExAblate...
                                                                                                                                                                                            Mar 03, 2015 - Sep 03, 2016 Brain Program
                                                                                                                                                                                            Back & neck pain Treatment of facetogenic lumbar back pain
                                                                                                                                                                                              Mar 02, 2015 - Mar 01, 2016 Research Award
                                                                                                                                                                                              General, Cancer Sonodynamic therapy for treatment of C6 glioma in a rat model – Step 2: P...
                                                                                                                                                                                                Feb 12, 2015 - Feb 11, 2016 Brain Program
                                                                                                                                                                                                Brain, General Enhancement of FUS Mediated Delivery of Stem Cells to Brain
                                                                                                                                                                                                  Feb 01, 2015 - Jan 31, 2016 Research Award
                                                                                                                                                                                                  Parkinson’s Disease Focused Ultrasound for Increased Delivery of Intranasal DNA Nanoparticles to...
                                                                                                                                                                                                    Feb 01, 2015 - Jan 31, 2017 Research Award
                                                                                                                                                                                                    Brain tumors, General MR-Guided Ultrasound Neurosurgery for the Treatment of Brain Tumors
                                                                                                                                                                                                      Nov 10, 2014 - Nov 09, 2016 Brain Program
                                                                                                                                                                                                      Bone, Non-metastases Magnetic Resonance-Guided High Intensity Focused Ultrasound for Pain Management...
                                                                                                                                                                                                        Sep 12, 2014 - Sep 11, 2015 Research Award
                                                                                                                                                                                                        Microbubble cloud formation from ultrasound contrast agents during histotripsy...
                                                                                                                                                                                                          Aug 01, 2014 - Nov 30, 2015 Research Award
                                                                                                                                                                                                          General, Technology Image-guided Non-invasive Ultrasonic Thrombolysis Using Histotripsy
                                                                                                                                                                                                            Jul 01, 2014 - Jun 30, 2018 Research Award
                                                                                                                                                                                                            General, Technology Real-time 3D MR Thermometry for Focused Ultrasound Surgery
                                                                                                                                                                                                              Jul 01, 2014 - Jun 30, 2015 Research Award
                                                                                                                                                                                                              Brain, General Non-Invasive Treatment of Pediatric Neurological Disorders using MR-guided...
                                                                                                                                                                                                                Jul 01, 2014 - Jun 30, 2015 Research Award
                                                                                                                                                                                                                Page 1 of 2

                                                                                                                                                                                                                The Focused Ultrasound Foundation Newsletter

                                                                                                                                                                                                                Our newsletter delivers updates for clinicians, researchers and patients. Sign up and stay on top of the rapid advancements of this innovative medical technology.

                                                                                                                                                                                                                Sign Up  Read the Latest Issue

                                                                                                                                                                                                                Read The Tumor  by John Grisham

                                                                                                                                                                                                                From John Grisham, comes a story where today’s medical fiction could become tomorrow’s lifesaving reality.

                                                                                                                                                                                                                Download a Free eBook or Audiobook

                                                                                                                                                                                                                Contact Details

                                                                                                                                                                                                                Call Us
                                                                                                                                                                                                                434.220.4993
                                                                                                                                                                                                                Find Us
                                                                                                                                                                                                                Focused Ultrasound Foundation
                                                                                                                                                                                                                1230 Cedars Court, Suite 206 Charlottesville, VA 22903
                                                                                                                                                                                                                Email