Foundation Funded Research Projects

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Showing 100 out of 159 research projects
Category Project Name (Click on the project name for more info) Primary Research Site Principal Investigator Funding Dates Program
A Study to Evaluate the Safety and Feasibility of Blood-Brain Barrier...
    Oct 31, 2019 - Oct 30, 2021 Brain Program
    Alzheimer’s Disease A Phase I/IIa Study: Feasibility of Blood-Brain Barrier Opening in the...
      Oct 30, 2019 - Oct 29, 2021 Brain Program
      MRI Guidance of Focused Ultrasound Neurosurgery
        Oct 24, 2019 - Jan 24, 2022 Brain Program
        MRI of Skull Heating During Focused Ultrasound Neurosurgery
          Oct 24, 2019 - Jan 24, 2022 Brain Program
          Development of Novel Acoustic Coupling Media to Improve Image Guidance and...
            Oct 24, 2019 - Jan 24, 2021 Research Award
            Focused ultrasound stimulation of the immune response in cancer models
              Oct 16, 2019 Immunotherapy
              Focused ultrasound stimulation of the immune response in a breast cancer model
                Oct 16, 2019 Immunotherapy
                Transcranial Histotripsy for Treatment of Brain Tumors – Initial In-vivo Pig S...
                  Oct 01, 2019 - Sep 30, 2020 Brain Program
                  Investigating the Feasibility of Targeting Temporal Lobe using Transcranial...
                    Sep 13, 2019 - Sep 12, 2020 Brain Program
                    Blood Brain Barrier (BBB) Opening of Rat by Laser-generated Focused Ultrasound...
                      Sep 10, 2019 - Mar 10, 2021 Brain Program
                      Non-Invasive Surgical Treatment of Lung Cancer
                        May 21, 2019 - Jul 20, 2020 Research Award
                        FUS for therapy of Neuromyelitis Optica – an inflammatory demyelinating d...
                          Mar 25, 2019 - Mar 24, 2020 Research Award
                          Brain tumors, Glioblastoma Focused ultrasound immunomodulation for pancreatic cancer
                            Mar 12, 2019 - Mar 12, 2020 Immunotherapy
                            Brain, General Microbubble enhanced FUS treatments in the brain: impact of bubble distribution...
                              Mar 01, 2019 - Mar 01, 2020 Brain Program
                              Convective skin-cooling device for use with existing MRgFUS systems to prevent...
                                Feb 28, 2019 - Nov 01, 2019 Research Award
                                Microbubble distribution in the brain: a real-time intra-operative map to...
                                  Feb 21, 2019 - Feb 21, 2020 Brain Program
                                  Parkinson’s Disease MRGFUS GENE DELIVERY FOR NEUROPROTECTION IN PARKINSON'S DISEASE
                                      Jan 18, 2019 - Jan 18, 2020 Brain Program
                                      Development of a turnkey USgFUS preclinical research platform
                                        Jan 04, 2019 - Jan 03, 2020 Research Award
                                        Drug delivery strategies using drug-loaded extracellular vesicles generated by...
                                          Dec 11, 2018 - Dec 10, 2019 Research Award
                                          Movement Disorders, General Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy for Tremor...
                                            Sep 28, 2018 - Sep 27, 2019 Research Award
                                            Psychiatric disorders A Phase 1 Trial of MR-guided Focused Ultrasound (MRgFUS) Bilateral Capsulotomy...
                                              Sep 27, 2018 - Sep 26, 2020 Brain Program
                                              Non-invasive varicose vein treatment by HIFU under ultrasound guidance: Phase...
                                                Sep 13, 2018 - Sep 12, 2019 Research Award
                                                Liver tumors Non-invasive Focused Ultrasound Ablation for the Treatment of...
                                                  Sep 13, 2018 - Aug 30, 2020 Research Award
                                                  Brain tumors, General Safety study: sonodynamic therapy with 5-ALA in a porcine model
                                                    Jun 05, 2018 - Jun 05, 2019 Brain Program
                                                    Psychiatric disorders Phase I trial of MR-guided Focused Ultrasound (MRgFUS) bilateral capsulotomy...
                                                      Jun 05, 2018 - Jun 04, 2020 Brain Program
                                                      Brain tumors, Glioblastoma Safety evaluation of irinotecan delivery to a rat glioma model using a clinical...
                                                        Jun 04, 2018 - Aug 04, 2019 Research Award
                                                        Epilepsy Focused ultrasound thalamotomy for the prevention of secondary generalization...
                                                          Jun 01, 2018 - May 31, 2018 Brain Program
                                                          Brain tumors, General Microvascular Ablation of Intracranial Gliomas with Focused Ultrasound (9L Line)
                                                            Apr 24, 2018 - Apr 24, 2019 Brain Program
                                                            Brain tumors, General Microvascular Ablation of Intracranial Gliomas with Focused Ultrasound (F98...
                                                                Apr 06, 2018 - Apr 06, 2019 Brain Program
                                                                Stroke, Thromboembolic Selective opening of the blood brain barrier using focused ultrasound combined...
                                                                  Apr 04, 2018 - Apr 04, 2019 Brain Program
                                                                  Brain, General Sonodynamic therapy for treatment of C6 glioma in a rat model proof-of-concept...
                                                                    Apr 04, 2018 - Oct 04, 2018 Brain Program
                                                                    Brain, General Focused ultrasound for treatment of deep-seated cerebral cavernous malformations
                                                                      Mar 26, 2018 - Mar 26, 2019 Brain Program
                                                                      Epilepsy Use of low-intensity focused ultrasound for the non-invasive, focal...
                                                                        Mar 18, 2018 - Jun 18, 2018 Research Award
                                                                        Soft tissue tumors Investigation of the immunostimulatory response to high intensity focused...
                                                                          Mar 12, 2018 - Mar 12, 2019 Veterinary
                                                                          Back & neck pain Focused ultrasound mediated neuromodulation for the treatment of spinal cord...
                                                                            Mar 05, 2018 - Mar 05, 2019 Brain Program
                                                                            Investigation of focused ultrasound mediated enhancement of chronic non-...
                                                                              Feb 12, 2018 - Feb 12, 2019 Veterinary
                                                                              General, Technology Laser-generated Focused Ultrasound Transducer for Transcranial Applications
                                                                                Feb 08, 2018 - Apr 22, 2019 Brain Program
                                                                                General, Technology Use of shock-wave exposures for accelerating thermal ablation of targeted...
                                                                                  Feb 07, 2018 - Apr 06, 2019 Research Award
                                                                                  Bladder tumors Focused Ultrasound Mediated Drug Delivery across the Urothelium
                                                                                    Feb 06, 2018 - Feb 05, 2019 Research Award
                                                                                    Pancreatic tumors Focused Ultrasound Driven Drug Release From Theranostic Nanoparticles For The...
                                                                                      Jan 24, 2018 - Jan 24, 2019 Research Award
                                                                                      Accessibility and Benefit of FUS treatment for inoperable Lung Cancer Patients,...
                                                                                        Dec 14, 2017 - Feb 13, 2019 Research Award
                                                                                        Alzheimer’s Disease Effects of FUS on CNS Uptake and Efficacy of an Anti-Amyloid Antibody in Aged...
                                                                                          Nov 30, 2017 - Mar 30, 2018 Research Award
                                                                                          Acoustic Backscatter-based 3D Mapping of Cavitation and Skull Surface in...
                                                                                            Oct 31, 2017 - Dec 31, 2018 Research Award
                                                                                            Back & neck pain Safety and initial feasibility of using the Neurolyser XR device for the...
                                                                                              Sep 26, 2017 - Mar 25, 2019 Research Award
                                                                                              Parkinson’s Disease MRgFUS Blood-Brain Barrier Drug Delivery with AAV2 Gene Therapy Microbubble...
                                                                                                Sep 01, 2017 - Aug 31, 2018 Research Award
                                                                                                Safety and Effectiveness of Sacroiliac Joint Palliation in Swine using MRgFUS
                                                                                                  Jul 01, 2017 - Jun 30, 2018 Research Award
                                                                                                  Bone, Non-metastases Comparative Study - FUS vs. RF ablation
                                                                                                    Jun 01, 2017 - May 31, 2020 Liver/Pancreas Program
                                                                                                    Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                                      May 17, 2017 - Nov 17, 2017 Immunotherapy
                                                                                                      Brain tumors, Metastasis Focused Ultrasound to Enhance Immunotherapy for Metastatic Brain Melanoma
                                                                                                        May 05, 2017 - Sep 04, 2018 Immunotherapy
                                                                                                        Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                                          May 01, 2017 - Nov 01, 2017 Immunotherapy
                                                                                                          Parkinson’s Disease A Prospective, Randomized, Sham Controlled Study to Evaluate the Safety and...
                                                                                                            Mar 01, 2017 - Sep 01, 2020 Brain Program
                                                                                                            Patterning of bone regeneration via ultrasound activation of heat shock-...
                                                                                                              Mar 01, 2017 - Feb 28, 2018 Research Award
                                                                                                              Brain tumors, General A Feasibility Safety Study Using the ExAblate 4000 system in Management of...
                                                                                                                Feb 27, 2017 - Feb 26, 2019 Brain Program
                                                                                                                Acoustic Parameters of Bone as a function of HU and MRI
                                                                                                                  Feb 20, 2017 - Feb 21, 2018 Brain Program
                                                                                                                  Neuropathic pain Phase 1 Clinical Trial of MR Guided Focused Ultrasound (FUS) Thalamotomy of...
                                                                                                                    Jan 19, 2017 - Jul 19, 2019 Brain Program
                                                                                                                    Alzheimer’s Disease A Study to Evaluate the Safety and Feasibility of Blood-Brain Barrier (BBB)...
                                                                                                                      Jan 12, 2017 - Jan 11, 2019 Brain Program
                                                                                                                      Real-time Treatment Monitoring by Diffusion MRI
                                                                                                                        Nov 29, 2016 - Nov 28, 2017 Brain Program
                                                                                                                        Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                                                          Nov 29, 2016 - May 19, 2017 Brain Program
                                                                                                                          Ultrasound-induced immune response on breast cancer
                                                                                                                            Nov 28, 2016 Immunotherapy
                                                                                                                            Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                                                              Nov 07, 2016 Brain Program
                                                                                                                              Brain, General FUS-mediated Neuromodulation from Unanesthetized Freely-moving Animals
                                                                                                                                Oct 01, 2016 - Sep 30, 2017 Research Award
                                                                                                                                Pancreatic tumors Defining Basic Properties of Physical Immunotherapy using HIFU and Immune...
                                                                                                                                  Sep 07, 2016 - Jun 07, 2019 Immunotherapy
                                                                                                                                  Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                                                                    Aug 15, 2016 - Feb 15, 2017 Immunotherapy
                                                                                                                                    Parkinson’s Disease Antibody Delivery Through the BBB Opening in an Alpha-Synuclein Model
                                                                                                                                      Aug 15, 2016 - Oct 15, 2017 Brain Program
                                                                                                                                      Massively Parallel Nonlinear Ultrasound Simulation of Histotripsy in the Brain
                                                                                                                                        Jul 18, 2016 - Jul 18, 2017 Brain Program
                                                                                                                                        Liver tumors A novel genetic reprogramming therapy for hepatocellular carcinoma using...
                                                                                                                                          Jul 01, 2016 - Jun 30, 2017 Veterinary
                                                                                                                                          Epilepsy A Feasibility Study to Evaluate Safety and Initial Effectiveness or MR-Guided...
                                                                                                                                            Jun 16, 2016 - Jun 16, 2018 Brain Program
                                                                                                                                            Brain tumors, Glioblastoma Ultrasound-mediated delivery of siRNA for enhancing temozolomide efficacy...
                                                                                                                                              Jun 01, 2016 - Dec 15, 2017 Research Award
                                                                                                                                              Parkinson’s Disease Minimally-Invasive Therapy for Parkinson’s Disease Achieved by the Focused U...
                                                                                                                                                Feb 04, 2016 - Feb 03, 2017 Brain Program
                                                                                                                                                Alzheimer’s Disease Effects of FUS on CNS Uptake and Efficacy of an Anti-Amyloid Antibody in Aged...
                                                                                                                                                  Feb 01, 2016 - Jan 31, 2017 Brain Program
                                                                                                                                                  Brain, General Development and Calibration of MR Techniques for In-Vivo Bone Thermometry
                                                                                                                                                    Feb 01, 2016 - Aug 16, 2018 Brain Program
                                                                                                                                                    General, Cancer Ultrasound ablation combined with immunotherapy: priming to enhance efficacy
                                                                                                                                                      Feb 01, 2016 - Jan 31, 2017 Brain Program
                                                                                                                                                      Brain, General Neuro Focused Ultrasound MR Coil Fabrication and Testing
                                                                                                                                                        Jan 06, 2016 - Apr 06, 2018 Brain Program
                                                                                                                                                        Kidney tumors Evaluation of the Systemic Response to Boiling Histotripsy Treatment for Renal...
                                                                                                                                                          Dec 01, 2015 - Apr 30, 2017 Research Award
                                                                                                                                                          Brain tumors, General A Chronic Pig Study of Transcranial Histotripsy for Treatment of Brain Tumors
                                                                                                                                                            Nov 11, 2015 - Dec 18, 2015 Brain Program
                                                                                                                                                            General, Cancer The Focused ultrasound mediated immune responses in metastatic melanoma
                                                                                                                                                              Nov 01, 2015 - Nov 01, 2017 Brain Program
                                                                                                                                                              Brain, General Neuronavigation-guided and Ultrasound-Monitored Human BBB-opening Focused...
                                                                                                                                                                Nov 01, 2015 - Oct 31, 2016 Brain Program
                                                                                                                                                                Brain, General Transcranial Histotripsy for Treatment of Brain Tumors
                                                                                                                                                                  Oct 21, 2015 - Feb 21, 2016 Brain Program
                                                                                                                                                                  Brain, General Method for fully 3D volumetric thermometry, with application to transcranial...
                                                                                                                                                                    Oct 09, 2015 - Oct 08, 2016 Brain Program
                                                                                                                                                                    Bone, Non-metastases Pediatric Focused Ultrasound Computational Data Center and Registry
                                                                                                                                                                      Oct 01, 2015 - Dec 31, 2017 Research Award
                                                                                                                                                                      Back & neck pain Low Intensity Pulsed Ultrasound (LIPUS) for the Treatment of Spinal Disc...
                                                                                                                                                                        Oct 01, 2015 - Sep 30, 2016 Research Award
                                                                                                                                                                        Brain, General Thermal Dose Experiment in a Pig Model
                                                                                                                                                                          Jul 24, 2015 - Feb 19, 2016 Brain Program
                                                                                                                                                                          Movement Disorders, General Modulated focused ultrasound for treatment of de-myelinating axons in multiple...
                                                                                                                                                                            Jun 01, 2015 - Nov 30, 2016 Research Award
                                                                                                                                                                            Atrial Fibrillation Trans-Esophageal Cardiac Ablation Using High Intensity Focused Ultrasound: A...
                                                                                                                                                                              Jun 01, 2015 - Nov 30, 2016 Research Award
                                                                                                                                                                              Parkinson’s Disease A feasibility Study to Evaluate Safety and Initial Effectiveness of ExAblate...
                                                                                                                                                                                  Mar 03, 2015 - Sep 03, 2016 Brain Program
                                                                                                                                                                                  Back & neck pain Treatment of facetogenic lumbar back pain
                                                                                                                                                                                    Mar 02, 2015 - Mar 01, 2016 Research Award
                                                                                                                                                                                    General, Cancer Sonodynamic therapy for treatment of C6 glioma in a rat model – Step 2: P...
                                                                                                                                                                                      Feb 12, 2015 - Feb 11, 2016 Brain Program
                                                                                                                                                                                      Parkinson’s Disease Focused Ultrasound for Increased Delivery of Intranasal DNA Nanoparticles to...
                                                                                                                                                                                        Feb 01, 2015 - Jan 31, 2017 Research Award
                                                                                                                                                                                        Brain, General Enhancement of FUS Mediated Delivery of Stem Cells to Brain
                                                                                                                                                                                          Feb 01, 2015 - Jan 31, 2016 Research Award
                                                                                                                                                                                          Brain tumors, General MR-Guided Ultrasound Neurosurgery for the Treatment of Brain Tumors
                                                                                                                                                                                            Nov 10, 2014 - Nov 09, 2016 Brain Program
                                                                                                                                                                                            Bone, Non-metastases Magnetic Resonance-Guided High Intensity Focused Ultrasound for Pain Management...
                                                                                                                                                                                              Sep 12, 2014 - Sep 11, 2015 Research Award
                                                                                                                                                                                              Microbubble cloud formation from ultrasound contrast agents during histotripsy...
                                                                                                                                                                                                Aug 01, 2014 - Nov 30, 2015 Research Award
                                                                                                                                                                                                General, Technology Image-guided Non-invasive Ultrasonic Thrombolysis Using Histotripsy
                                                                                                                                                                                                  Jul 01, 2014 - Jun 30, 2018 Research Award
                                                                                                                                                                                                  Brain, General Non-Invasive Treatment of Pediatric Neurological Disorders using MR-guided...
                                                                                                                                                                                                    Jul 01, 2014 - Jun 30, 2015 Research Award
                                                                                                                                                                                                    General, Technology Real-time 3D MR Thermometry for Focused Ultrasound Surgery
                                                                                                                                                                                                      Jul 01, 2014 - Jun 30, 2015 Research Award
                                                                                                                                                                                                      General, Cancer Sonodynamic therapy for treatment of C6 glioma in a rat model – Step 1: F...
                                                                                                                                                                                                        Jun 03, 2014 - Sep 03, 2014 Brain Program
                                                                                                                                                                                                        Brain, General MR Temperature Imaging Toolbox for Focused Ultrasound Neurosurgery
                                                                                                                                                                                                          Jun 01, 2014 - May 31, 2016 Research Award
                                                                                                                                                                                                          Uterine fibroids Accelerated focused ultrasound ablation of uterine fibroids with MR guided...
                                                                                                                                                                                                              Jun 01, 2014 - May 31, 2016 Research Award
                                                                                                                                                                                                              General, Cancer Feasibility of MR guided Lung Cancer ablation using saline flooded lung
                                                                                                                                                                                                                Jun 01, 2014 - Aug 31, 2015 Research Award
                                                                                                                                                                                                                Head and neck cancer Magnetic Resonance Guided High Intensity Focused Ultrasound for Head and Neck...
                                                                                                                                                                                                                  Dec 01, 2013 - Jun 01, 2016 Research Award
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