The Foundation considers the brain to be the vanguard target for focused ultrasound.

Given the challenges of accessing the brain and the high cost and limitations of some current approaches, we believe that this non-invasive technology has the potential to revolutionize the treatment of many brain disorders.

Focused ultrasound has the potential to:

  • transform treatment by gaining access deep within the brain without harming healthy tissue;
  • ablate targeted tissue without exposing the brain to the effects of ionizing radiation; and
  • enable the reversible opening of the blood-brain barrier to deliver therapeutic agents to targeted diseased areas.

Thermal Ablation Targets with signaturesThe Foundation’s Brain Program convenes experts around the globe to accelerate research and development of the technology for a range of disorders. The program helps to identify and overcome technical challenges, optimize the technology, and create a strategic pathway of advancing clinical research. We are currently working with leading U.S. neurosurgery research centers to advance focused ultrasound for several movement disorders. The publication of focused ultrasound treatment for essential tremor in the New England Journal of Medicine is an incredible milestone for our brain program and demonstrates the potential of the technology.

Results from an essential tremor pivotal trial were published in 2016, leading to the first FDA approval to treat a neurological condition with focused ultrasound.

Clinical Trials

Patient participation in clinical trials is critical to advancing focused ultrasound treatment for brain disorders. Clinical research is ongoing for the treatment of brain tumorsessential tremor, and Parkinson's disease. 

Learn more about focused ultrasound for: 

clinical stages key

Addiction, Opioid Clinical Trials icon  
Addiction, Other Early Stage icon  
Alzheimer's Disease Clinical Trials icon  
Amyotrophic Lateral Sclerosis (ALS) Clinical Trials icon  
Anorexia Nervosa Early Stage icon  
Attention Deficit Hyperactivity Disorder (ADHD) Clinical Trials icon  
Brain Tumors, Glioma and Metastatic Clinical Trials icon  
Cerebral Cavernous Malformations Early Stage icon  
Dementia Clinical Trials icon  
Depression Outside Approval icon Clinical Trials icon
Clinical Trials icon  
Epilepsy Clinical Trials icon  
Essential Tremor FDA Approved icon Outside Approval icon
Early Stage icon  
Holmes Tremor
Clinical Trials icon  
Huntington's Disease Clinical Trials icon  
Hydrocephalus Early Stage icon  
Mood Disorder Clinical Trials icon  
Multiple Sclerosis Clinical Trials icon  
Neuroblastoma Clinical Trials icon  
Neuropathic Pain Outside Approval icon Clinical Trials icon
Neuropathy Clinical Trials icon  
Obsessive-Compulsive Disorder (OCD) Outside Approval icon Clinical Trials icon
Painful Amputation Neuromas
Clinical Trials icon  
Parkinson's Disease FDA Approved icon Outside Approval icon Clinical Trials icon
Rett Syndrome Early Stage icon  
Schizophrenia Clinical Trials icon  
Stroke, Intracerebral Hemorrhage Early Stage icon  
Stroke, Thromboembolic Early Stage icon  
Traumatic Brain Injury Clinical Trials icon  
Tremor, Orthostatic Clinical Trials icon  
Trigeminal Neuralgia Outside Approval icon Clinical Trials icon


The Focused Ultrasound Foundation Newsletter

Our newsletter delivers updates for clinicians, researchers and patients. Sign up and stay on top of the rapid advancements of this innovative medical technology.

Sign Up  Read the Latest Issue

Read The Tumor  by John Grisham

From John Grisham, comes a story where today’s medical fiction could become tomorrow’s lifesaving reality.

Download a Free eBook or Audiobook

Contact Details

Call Us
Find Us
Focused Ultrasound Foundation
1230 Cedars Court, Suite 206 Charlottesville, VA 22903
Whitelist Instructions