Focused Ultrasound Therapy

arly Stage square

Focused ultrasound is an early-stage, non-invasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients in need of dental bonding. This novel technology focuses beams of ultrasound energy precisely and accurately on targets in the body without damaging surrounding normal tissue. Where the beams converge, the ultrasound produces precise ablation (thermal destruction of tissue) enabling dental bonding to be occur without the need for acid products. While significant preclinical work has been accomplished, there is still much to be done before this technology will be widely available.

The primary options for treatment of bonding includes use of acid agents, which also removes important dental components that aid in bonding. The result is that after cleaning, the dentist may have to create grooves for bonding, resulting in decreased remaining tooth.

For certain patients, focused ultrasound could provide a non-invasive alternative to existing techniques, and preserve more of the patients tooth.


  • Focused ultrasound is non-invasive, so it does not carry added concerns associated with acid agents.
  • Focused ultrasound can reach the desired target without damaging surrounding tissue.
  • It can be repeated, if necessary.

Clinical Trials

At the present time, there are no clinical trials recruiting patients for focused ultrasound dental bonding treatments.

Regulatory Approval and Reimbursement 

Focused ultrasound treatment for dental bonding is not yet approved by regulatory bodies or covered by medical insurance companies.

Notable Papers

Daood U, Fawzy AS. Minimally invasive high-intensity focused ultrasound (HIFU) improves dentine remineralization with hydroxyapatite nanorods. Dent Mater. 2020 Jan 30. pii: S0109-5641(20)30005-1. doi: 10.1016/

Fawzy AS, Daood U, Matinlinna JP.Potential of high-intensity focused ultrasound in resin-dentine bonding. Dent Mater.  2019 Apr 16. pii: S0109-5641(18)31394-0. doi: 10.1016/ 

Daood U, Fawzy AS. Macrophage response and surface analysis of dental cementum after treatment with high intensity focused ultrasound. Arch Oral Biol. 2019 Feb;98:195-203. doi: 10.1016/j.archoralbio.2018.10.019. Epub 2018 Nov 19.

Click here for additional references from PubMed.


The Focused Ultrasound Foundation Newsletter

Our newsletter delivers updates for clinicians, researchers and patients. Sign up and stay on top of the rapid advancements of this innovative medical technology.

Sign Up  Read the Latest Issue

Read The Tumor  by John Grisham

From John Grisham, comes a story where today’s medical fiction could become tomorrow’s lifesaving reality.

Download a Free eBook or Audiobook

Contact Details

Call Us
Find Us
Focused Ultrasound Foundation
1230 Cedars Court, Suite 206 Charlottesville, VA 22903