Focused Ultrasound Surgery Foundation

Principal Investigator: Katherine Whittaker Ferrara, Ph.D., Professor of Biomedical Engineering, University of California, Davis

Abstract:  We have observed that low-mechanical index ultrasound can enhance drug accumulation and transport in a clinically-relevant protocol and have devised systems to precisely quantify full-body biodistribution of drugs before and after ultrasound and to precisely control the ultrasound parameters and the resulting heating. We will combine these methods to optimize the ultrasound dose, to quantify the resulting biodistribution of drug and to assess efficacy.