FUSF Funded Research Projects

Robust MR thermometry for MRgHIFU in breast and liver

Principal Investigator: Nick Todd, Ph.D., Post-doctoral Researcher, Department of Radiology, University of Utah

Co-Investigators: Dennis Parker, Ph.D., Professor of Radiology, University of Utah; Rares Salomir, Ph.D., Research Scientist, University of Geneva

Award: $100,000

Funding Period: June 1, 2010 - September 30, 2011

Abstract: The aim of this proposal is to implement MR temperature measurement techniques that accelerate data acquisition speed and are robust to motion-related errors. Collaboration between the research groups at the University of Utah and the University of Geneva will facilitate the transmission, implementation, and further development of these site-specific MR temperature measurement techniques and will accelerate the two goups' respective goals of using MRgHIFU to treat tumors in breast and liver.

Progress Report: 6-month progress report; Final progress report

Publications:

1. The effects of spatial sampling choices on MR temperature measurements

2. Reconstruction of fully 3-D high spatial and temporal resolution MR temperature maps for retrospective applications

• < Development and clinical evaluation of MR-guided focused ultrasound for tattooing tumors
• MRI-guided localized delivery of chemotherapy using temperature-sensitive liposomes and HIFU >