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FUSF Funded Research Projects

Heterogeneity correction for improved breast cancer ablation

Principal Investigator: Mario Ries, Ph.D., Research Engineer, Laboratory for Functional and Molecular Imaging (IMF), Bordeaux

Co-investigators: Christ Moonen, Ph.D., Laboratory Director, IMF, Bordeaux; Baudouin Denis de Senneville, Ph.D., IMF, Bordeaux; Charles Mougenot, Ph.D., Research Engineer, Philips Healthcare

Award: $100,000

Funding Period: February 1, 2011 - January 31, 2012

Abstract: The treatment of breast cancer by MR guided HIFU has recently shown great potential for clinical practice. Although innovative lateral firing transducer designs allow to significantly reduce the risk of undesired tissue damage to the thoracic cage, the heart and the lung, such a design is typically limited by the aberration effect of the inhomogeneous tissue composition of the breast. This project proposes a correction strategy for this type of aberrations, based on high resolution MRI in conjunction with tissue ultrasound celerity measurements. The method is compatible with clinical practice and has the potential to lead to improved treatment efficiency and increased patient safety for MR guided HIFU-ablations of breast cancer.

Progress Reports: 6-month progress report

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