Training Site: Department of Radiology, St. Mary’s Hospital, Imperial College, London

Mentor: Wladyslaw Gedroyc, M.D.

Fellowship Period: July 2009 – June 2010

I am a trained anesthetist currently working in the UK and my intention is to specialize in pain management as a career path. I have been involved in several projects in the field of pain management already, and following discussions with the pain management team at St. Mary's and Professor Gedroyc from Radiology, I am extremely keen to work on the evolving project that is being developed at St. Mary's for the treatment of facet joint pain using MR-guided focused ultrasound. There is a large practice of facet joint injections and facet joint radiofrequency (RF) ablation already in place at St. Mary's with up to 12 such procedures being carried out every week as pain control for the common problem of facet related back pain. The project will be to utilize focused ultrasound to perform noninvasive facet joint ablations using MR control withthe goal of replacing more invasive percutaneous RF ablation procedures.

Progress Reports: 6-month progress report; Final progress report

Training Site: Department of Radiology, University of California, Los Angeles

Mentors: David Lu, M.D.; Steven Raman, M.D.

Fellowship Period: July 2008 – June 2009

Dr. McClure recently changed from residency in urology to radiology at the University of California, Los Angeles. His transition stems in large part due to the promising possibilities that exist in minimally invasive image-guided treatments for a variety of malignancies, especially MRgFUS. During his transition year, Dr. McClure will work with clinicians and researchers in the development of MRgFUS at UCLA. This includes working with Dr. David Lu and Dr. Steve Raman for treatment of uterine fibroids as well as clinical trials investigating the use of MRgFUS in metastatic bone tumors, prostate cancer, and breast cancer. This fellowship will provide him the opportunity to develop a better understanding of MRgFUS and to be involved in the development of this new and exciting technology.

Progress Reports: 6-month progress report; Final progress report

Training Site: Department of Neurosurgery, SHEBA Medical Center, Tel Hashomer, Israel

Mentors: Sagi Harnof, M.D.; Zvi Cohen, M.D.

Fellowship Period: March 2008 – February 2009

I'm currently a Neurosurgery resident in Sheba Medical Center Tel Hashomer Israel (PGY5). I have a 6-12 month period starting on January 2008 that I would like to dedicate to High Intensity Focused Ultrasound research. I have been exposed to HIFU technology during my residency (by working with Drs. Harnof and Cohen). The fields of research I would like to participate include:

• Neuro-Vascular
• Neuro-Oncology
• Drug delivery
• Brain response to HIFU

I hope I will have the chance to perform preclinical as well as clinical research. Since I have two more years to complete my residency in Sheba, I will be able to complete and continue any project that will start in the fellowship dedicated period. In the future, once completing the residency program, I would like to do a Fellowship program in the area of brain tumors and functional neurosurgery. In both fields I can see the utility of HIFU technology and my personal involvement.

Progress Report: Final progress report